2. Metabolic Enzyme/Protease
  3. Drug Metabolite
  4. Ribociclib acetate

Ribociclib acetate is a degradation product of Ribociclib (HY-15777) under acid-base hydrolysis conditions. Ribociclib acetate has been predicted to be carcinogenic.

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Ribociclib acetate Chemical Structure

Ribociclib acetate Chemical Structure

CAS No. : 2762182-61-4

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Ribociclib acetate Related Antibodies

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Description

Ribociclib acetate is a degradation product of Ribociclib (HY-15777) under acid-base hydrolysis conditions. Ribociclib acetate has been predicted to be carcinogenic[1].

Molecular Weight

407.47

Formula

C21H25N7O2
CAS No.
SMILES

O=C(C1=CC2=C(N1C3CCCC3)N=C(NC4=NC=C(N5CCNCC5)C=C4)N=C2)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 4 mg/mL (9.82 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4542 mL 12.2708 mL 24.5417 mL
5 mM 0.4908 mL 2.4542 mL 4.9083 mL
View the Complete Stock Solution Preparation Table

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4542 mL 12.2708 mL 24.5417 mL 61.3542 mL
5 mM 0.4908 mL 2.4542 mL 4.9083 mL 12.2708 mL
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Ribociclib acetate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ribociclib2762182-61-4Drug MetaboliteInhibitorinhibitorinhibit

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