Riboflavin phosphate sodium hydrate  (Synonyms: Riboflavine phosphate sodium hydrate; Riboflavin 5'-phosphate sodium hydrate; Riboflavine 5'-phosphate sodium hydrate)

Riboflavine phosphate sodium hydrate (Riboflavine 5'-phosphate sodium hydrate) is a derivative of Riboflavin (vitamin B2) which is an essential nutrient for animals. Riboflavine phosphate sodium hydrate can be used for the research of progressive keratoconus, corneal ectasia and irregular astigmatism^[1][2]. Riboflavine phosphate sodium hydrate is a very effective NAD⁺-recycling agent^[3].

Riboflavine phosphate sodium hydrate is clearly a very effective NAD⁺-recycling agent with good yields of the cyclohexanone product accompanied by high levels of NAP turnover being achieved routinely^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

514.36

C₁₇H₂₄N₄NaO₁₁P

6184-17-4

Solid

Light yellow to orange

CC1=CC2=C(C=C1C)N=C(C(N2C[C@@H]([C@@H]([C@@H](COP(O)(O[Na])=O)O)O)O)=N3)C(NC3=O)=O.O.O

Room temperature in continental US; may vary elsewhere.

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

• [1]. José Luis Revuelta, et al. Bioproduction of riboflavin: a bright yellow history. J Ind Microbiol Biotechnol. 2017 May;44(4-5):659-665.  [Content Brief]

  [2]. Carmine Ostacolo, et al. Enhancement of corneal permeation of riboflavin-5'-phosphate through vitamin E TPGS: a promising approach in corneal trans-epithelial cross linking treatment. Int J Pharm. 2013 Jan 20;440(2):148-53.  [Content Brief]

  [3]. J.Bryan Jones, et al. Nicotinamide coenzyme regeneration. Flavin mononucleotide (riboflavin phosphate) as an efficient, economical, and enzyme-compatible recycling agent. Can J Chem. 1976, 54(19): 2969-2973,