2. Apoptosis
  3. RIP kinase Necroptosis
  4. RIPK1-IN-12

RIPK1-IN-12 is a potent RIPK1 inhibitor. RIPK1-IN-12 inhibits necroptosis in both human and mouse cells, with EC50 values of 1.6 and 2.9 nM, respectively.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

RIPK1-IN-12 Chemical Structure

RIPK1-IN-12 Chemical Structure

CAS No. : 2173556-92-6

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RIPK1-IN-12 Related Antibodies

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Description

RIPK1-IN-12 is a potent RIPK1 inhibitor. RIPK1-IN-12 inhibits necroptosis in both human and mouse cells, with EC50 values of 1.6 and 2.9 nM, respectively[1].

IC50 & Target

RIPK1[1]
In Vitro

RIPK1-IN-12 (Compound 58; 24 hours) demonstrates potent anti-necroptotic activity (EC50=1.6 nM in HT-29 cells and EC50= 2.9 nM in L929 cells)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

RIPK1-IN-12 Related Antibodies
Molecular Weight

450.55

Formula

C24H26N4O3S
CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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RIPK1-IN-12 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RIPK1-IN-122173556-92-6RIP kinaseNecroptosisReceptor-interacting protein kinasesRIPKnecroptosisinflammatoryHT-29L929 cellsInhibitorinhibitorinhibit

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