Risperidone-d₆ (Synonyms: R 64 766-d₆)

Cat. No.: HY-11018S2: FAQs
Data Sheet Handling Instructions

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Risperidone-d6 (R 64 766-d6) is the deuterium labeled Risperidone (HY-11018). Risperidone is a serotonin 5-HT₂ receptor blocker, P-Glycoprotein inhibitor and potent dopamine D₂ receptor antagonist, with K_is of 4.8, 5.9 nM for 5-HT_2A and dopamine D₂ receptor, respectively.

For research use only. We do not sell to patients.

Risperidone-d<sub>6</sub> Chemical Structure

Risperidone-d₆ Chemical Structure

CAS No. : 1225444-65-4

Size		Stock
1 mg		Get quote	Estimated Time of Arrival: December 31

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This product is a controlled substance and not for sale in your territory.

Other Forms of Risperidone-d₆:

Risperidone In-stock
Risperidone-d₄-1 Get quote

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•Related Small Molecules:

•Related Proteins:

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5-HT₁ Receptor 5-HT₂ Receptor 5-HT₃ Receptor 5-HT₄ Receptor 5-HT₅ Receptor 5-HT₆ Receptor 5-HT₇ Receptor 5-HT Receptor

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Dopamine Receptor D₁ Receptor D₂ Receptor D₃ Receptor D₄ Receptor D₅ Receptor

Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target^[1]^[2]

D₂ Receptor

5.9 nM (Ki)

5-HT_2A Receptor

4.8 nM (Ki)

Molecular Weight

416.52

Formula

C₂₃H₂₁D₆FN₄O₂

CAS No.

1225444-65-4

Unlabeled CAS

106266-06-2

SMILES

[2H]C([2H])(C1=C(C(N2CCCC([2H])(C2=N1)[2H])=O)CCN3CCC(CC3)C4=NOC5=C(C(F)=CC=C45)[2H])[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Nyberg S, et al. 5-HT2 and D2 dopamine receptor occupancy in the living human brain. A PET study with risperidone. Psychopharmacology (Berl). 1993;110(3):265-72. [Content Brief]

[2]. Chen ML, et al. Risperidone modulates the cytokine and chemokine release of dendritic cells and induces TNF-α-directed cell apoptosis in neutrophils. Int Immunopharmacol. 2012 Jan;12(1):197-204. [Content Brief]

Risperidone-d₆ Related Classifications

Neurological Disease

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Risperidone-d₆1225444-65-4R 64 766-d₆5-HT ReceptorDopamine ReceptorP-glycoproteinSerotonin Receptor5-hydroxytryptamine ReceptorP-gpPgpMultidrug resistance protein 1MDR1ATP-binding cassette sub-family B member 1ABCB1Cluster of differentiation 243CD243Inhibitorinhibitorinhibit

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Risperidone-d6 (Synonyms: R 64 766-d6)

Other Forms of Risperidone-d6:

Risperidone-d6 Related Antibodies