1. Epigenetics Stem Cell/Wnt Protein Tyrosine Kinase/RTK JAK/STAT Signaling
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  3. Ritlecitinib (malonate)

Ritlecitinib (malonate)  (Synonyms: PF-06651600 (malonate))

Cat. No.: HY-100754A
Handling Instructions

Ritlecitinib (PF-06651600) malonate is an orally active and selective JAK3 inhibitor with an IC50 of 33.1 nM. Ritlecitinib (malonate) can be used for the research of inflammatory and autoimmune diseases.

For research use only. We do not sell to patients.

Ritlecitinib (malonate) Chemical Structure

Ritlecitinib (malonate) Chemical Structure

CAS No. : 2140301-97-7

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Description

Ritlecitinib (PF-06651600) malonate is an orally active and selective JAK3 inhibitor with an IC50 of 33.1 nM. Ritlecitinib (malonate) can be used for the research of inflammatory and autoimmune diseases[1].

IC50 & Target

IC50: 33.1 nM (JAK3)[1]

Molecular Weight

389.41

Formula

C18H23N5O5

CAS No.
SMILES

OC(CC(O)=O)=O.C=CC(N1[C@@H](C)CC[C@@H](NC2=C3C(NC=C3)=NC=N2)C1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Ritlecitinib (malonate)
Cat. No.:
HY-100754A
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