2. Metabolic Enzyme/Protease
  3. Factor Xa
  4. Rivaroxaban-d4

Rivaroxaban-d4  (Synonyms: BAY 59-7939-d4)

Cat. No.: HY-50903S Purity: 98.91%
COA Handling Instructions

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Rivaroxaban-d4 is a deuterium labeled Rivaroxaban. Rivaroxaban is a highly potent，selective and direct Factor Xa (FXa) inhibitor, achieving a strong gain in anti-FXa potency (IC50 0.7 nM; Ki 0.4 nM)[1][2].

For research use only. We do not sell to patients.

Rivaroxaban-d<sub>4</sub> Chemical Structure

Rivaroxaban-d4 Chemical Structure

CAS No. : 1132681-38-9

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1 mg USD 300 In-stock
5 mg USD 690 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Rivaroxaban-d4:

Rivaroxaban-d4 Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Rivaroxaban-d4

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  • Purity & Documentation

  • References

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Description

Rivaroxaban-d4 is a deuterium labeled Rivaroxaban. Rivaroxaban is a highly potent，selective and direct Factor Xa (FXa) inhibitor, achieving a strong gain in anti-FXa potency (IC50 0.7 nM; Ki 0.4 nM)[1][2].

IC50 & Target

IC50: 0.7 nM (Factor Xa); Ki: 0.4 nM (Factor Xa)[1][2]
Molecular Weight

439.91

Formula

C19H14D4ClN3O5S
CAS No.
Unlabeled CAS

366789-02-8
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC=C(Cl)S1)NC[C@H]2CN(C3=C([2H])C([2H])=C(N4C(COCC4)=O)C([2H])=C3[2H])C(O2)=O
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (113.66 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 50 mg/mL (113.66 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2732 mL 11.3660 mL 22.7319 mL
5 mM 0.4546 mL 2.2732 mL 4.5464 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 2.2732 mL 11.3660 mL 22.7319 mL 56.8298 mL
5 mM 0.4546 mL 2.2732 mL 4.5464 mL 11.3660 mL
10 mM 0.2273 mL 1.1366 mL 2.2732 mL 5.6830 mL
15 mM 0.1515 mL 0.7577 mL 1.5155 mL 3.7887 mL
20 mM 0.1137 mL 0.5683 mL 1.1366 mL 2.8415 mL
25 mM 0.0909 mL 0.4546 mL 0.9093 mL 2.2732 mL
30 mM 0.0758 mL 0.3789 mL 0.7577 mL 1.8943 mL
40 mM 0.0568 mL 0.2841 mL 0.5683 mL 1.4207 mL
50 mM 0.0455 mL 0.2273 mL 0.4546 mL 1.1366 mL
60 mM 0.0379 mL 0.1894 mL 0.3789 mL 0.9472 mL
80 mM 0.0284 mL 0.1421 mL 0.2841 mL 0.7104 mL
100 mM 0.0227 mL 0.1137 mL 0.2273 mL 0.5683 mL
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Rivaroxaban-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rivaroxaban-d41132681-38-9BAY 59-7939-d4Factor XaFxaDeuteriumlabeledanti-FXapotencyInhibitorinhibitorinhibit

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