2. Cell Cycle/DNA Damage TGF-beta/Smad Stem Cell/Wnt Cytoskeleton
  3. ROCK
  4. ROCK2-IN-6 hydrochloride

ROCK2-IN-6 hydrochloride (Comp A) is a selective ROCK2 inhibitor, can be used for ROCK mediated diseases, autoimmune diseases and inflammation research.

For research use only. We do not sell to patients.

ROCK2-IN-6 hydrochloride Chemical Structure

ROCK2-IN-6 hydrochloride Chemical Structure

CAS No. : 2762238-94-6

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1 mg USD 150 In-stock
5 mg USD 300 In-stock
10 mg USD 480 In-stock
25 mg USD 950 In-stock
50 mg USD 1500 In-stock
100 mg USD 2400 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of ROCK2-IN-6 hydrochloride:

ROCK2-IN-6 hydrochloride Related Antibodies

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Description

ROCK2-IN-6 hydrochloride (Comp A) is a selective ROCK2 inhibitor, can be used for ROCK mediated diseases, autoimmune diseases and inflammation research[1].

Molecular Weight

521.95

Formula

C26H22ClF2N7O
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(N1CC(F)(C1)F)C2=CC3=C(N2C)C=C(C4=NC(NC5=CC=C(C6=CNN=C6)C=C5)=CC=N4)C=C3.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (239.49 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9159 mL 9.5795 mL 19.1589 mL
5 mM 0.3832 mL 1.9159 mL 3.8318 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9159 mL 9.5795 mL 19.1589 mL 47.8973 mL
5 mM 0.3832 mL 1.9159 mL 3.8318 mL 9.5795 mL
10 mM 0.1916 mL 0.9579 mL 1.9159 mL 4.7897 mL
15 mM 0.1277 mL 0.6386 mL 1.2773 mL 3.1932 mL
20 mM 0.0958 mL 0.4790 mL 0.9579 mL 2.3949 mL
25 mM 0.0766 mL 0.3832 mL 0.7664 mL 1.9159 mL
30 mM 0.0639 mL 0.3193 mL 0.6386 mL 1.5966 mL
40 mM 0.0479 mL 0.2395 mL 0.4790 mL 1.1974 mL
50 mM 0.0383 mL 0.1916 mL 0.3832 mL 0.9579 mL
60 mM 0.0319 mL 0.1597 mL 0.3193 mL 0.7983 mL
80 mM 0.0239 mL 0.1197 mL 0.2395 mL 0.5987 mL
100 mM 0.0192 mL 0.0958 mL 0.1916 mL 0.4790 mL
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ROCK2-IN-6 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ROCK2-IN-62762238-94-6ROCKRho-associated protein kinaseRho-associated kinaseRho-kinaseROKInhibitorinhibitorinhibit

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