2. Immunology/Inflammation Antibody-drug Conjugate/ADC Related
  3. Radionuclide-Drug Conjugates (RDCs) PSMA
  4. Rosopatamab

Rosopatamab  (Synonyms: HUJ-591)

Cat. No.: HY-P99239 Purity: 99.47%
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Rosopatamab (HuJ591) is a humanized antiPSMA IgG1 monoclonal antibody that can be used in cancer research, especially prostate cancer. Rosopatamab can be linked to the low-energy beta-emitting radioisotope lutetium-177 (177Lu) through the bifunctional chelator DOTA-NHS ester to obtain a radioimmunoconjugate that targets malignant prostate cells with high efficiency.

For research use only. We do not sell to patients.

CAS No. : 2260767-49-3

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1 mg USD 300 In-stock
5 mg USD 760 In-stock
10 mg USD 1200 In-stock
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Based on 1 publication(s) in Google Scholar

Rosopatamab Related Antibodies

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Description

Rosopatamab (HuJ591) is a humanized antiPSMA IgG1 monoclonal antibody that can be used in cancer research, especially prostate cancer. Rosopatamab can be linked to the low-energy beta-emitting radioisotope lutetium-177 (177Lu) through the bifunctional chelator DOTA-NHS ester to obtain a radioimmunoconjugate that targets malignant prostate cells with high efficiency[1].

Isotype

Human IgG1 kappa
Recommend Isotype Controls
Species

Chimeric
IC50 & Target

RDC Antibody

 

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Rosopatamab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Biological Activity
  • Immobilized Rosopatamab can bind Human PSMA/FOLH1 Protein (ECD, His Tag). The EC50 for this effect is 42.68 ng/mL.
Purity & Documentation

Purity: 99.47%

SDS (251 KB)

COA (231 KB) SDS-PAGE (134 KB)

Inhibitory Antibodies User Guide (602 KB)
References
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Rosopatamab Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rosopatamab2260767-49-3HUJ-591HUJ591HUJ 591Radionuclide-Drug Conjugates (RDCs)PSMAProstate-specific membrane antigencancerprostate cancerInhibitorinhibitorinhibit

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