2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. (RS)-AMPA hydrochloride

(RS)-AMPA hydrochloride  (Synonyms: (±)-AMPA hydrochloride)

Cat. No.: HY-100815E
Handling Instructions

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(RS)-AMPA ((±)-AMPA) hydrochloride is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS)-AMPA hydrobromide does not interfere with binding sites for kainic acid or NMDA receptors.

For research use only. We do not sell to patients.

(RS)-AMPA hydrochloride Chemical Structure

(RS)-AMPA hydrochloride Chemical Structure

CAS No. : 2922283-04-1

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5 mg USD 180 Ask For Quote & Lead Time
10 mg USD 290 Ask For Quote & Lead Time
25 mg USD 640 Ask For Quote & Lead Time

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Other Forms of (RS)-AMPA hydrochloride:

(RS)-AMPA hydrochloride Related Antibodies

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AMPA Receptor NMDA Receptor Kainate Receptor

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Description

(RS)-AMPA ((±)-AMPA) hydrochloride is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS)-AMPA hydrobromide does not interfere with binding sites for kainic acid or NMDA receptors[1][2].

Molecular Weight

222.63

Formula

C7H11ClN2O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1NOC(C)=C1CC(C(O)=O)N.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (561.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.4918 mL 22.4588 mL 44.9176 mL
5 mM 0.8984 mL 4.4918 mL 8.9835 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.4918 mL 22.4588 mL 44.9176 mL 112.2939 mL
5 mM 0.8984 mL 4.4918 mL 8.9835 mL 22.4588 mL
10 mM 0.4492 mL 2.2459 mL 4.4918 mL 11.2294 mL
15 mM 0.2995 mL 1.4973 mL 2.9945 mL 7.4863 mL
20 mM 0.2246 mL 1.1229 mL 2.2459 mL 5.6147 mL
25 mM 0.1797 mL 0.8984 mL 1.7967 mL 4.4918 mL
30 mM 0.1497 mL 0.7486 mL 1.4973 mL 3.7431 mL
40 mM 0.1123 mL 0.5615 mL 1.1229 mL 2.8073 mL
50 mM 0.0898 mL 0.4492 mL 0.8984 mL 2.2459 mL
60 mM 0.0749 mL 0.3743 mL 0.7486 mL 1.8716 mL
80 mM 0.0561 mL 0.2807 mL 0.5615 mL 1.4037 mL
100 mM 0.0449 mL 0.2246 mL 0.4492 mL 1.1229 mL
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(RS)-AMPA hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(RS)-AMPA2922283-04-1(±)-AMPAiGluRIonotropic glutamate receptorsDepolarizationsmotoneuronesinterneuronesglutamateCNSkainicL-glutamicneurotransmitterNMDAInhibitorinhibitorinhibit

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