(RS)-AMPA hydrochloride (Synonyms: (±)-AMPA hydrochloride)

Cat. No.: HY-100815E: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

(RS)-AMPA ((±)-AMPA) hydrochloride is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS)-AMPA hydrobromide does not interfere with binding sites for kainic acid or NMDA receptors.

For research use only. We do not sell to patients.

(RS)-AMPA hydrochloride Chemical Structure

CAS No. : 2922283-04-1

Size	Price	Stock
5 mg	USD 180	Ask For Quote & Lead Time
10 mg	USD 290	Ask For Quote & Lead Time
25 mg	USD 640	Ask For Quote & Lead Time

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other Forms of (RS)-AMPA hydrochloride:

(R)-AMPA Get quote
(RS)-AMPA Get quote

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•Related Small Molecules:

•Related Proteins:

View All iGluR Isoform Specific Products:

View All Isoforms

AMPA Receptor NMDA Receptor Kainate Receptor

Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

222.63

Formula

C₇H₁₁ClN₂O₄

CAS No.

2922283-04-1

Appearance

Solid

Color

White to off-white

SMILES

O=C1NOC(C)=C1CC(C(O)=O)N.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (561.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.4918 mL	22.4588 mL	44.9176 mL
5 mM	0.8984 mL	4.4918 mL	8.9835 mL
10 mM	0.4492 mL	2.2459 mL	4.4918 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.74%

Select Batch:

Data Sheet (273 KB) SDS (252 KB)

COA (253 KB) HNMR (249 KB) RP-HPLC (253 KB) MS (68 KB)

Handling Instructions (2659 KB)

References

[1]. Hösli L, et al. Effects of the glutamate analogue AMPA and its interaction with antagonists on cultured rat spinal and brain stem neurones. Neurosci Lett. 1983 Mar 28;36(1):59-62. [Content Brief]

[2]. Sommer B, et al. Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS. Science. 1990 Sep 28;249(4976):1580-5. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.4918 mL	22.4588 mL	44.9176 mL	112.2939 mL
	5 mM	0.8984 mL	4.4918 mL	8.9835 mL	22.4588 mL
	10 mM	0.4492 mL	2.2459 mL	4.4918 mL	11.2294 mL
	15 mM	0.2995 mL	1.4973 mL	2.9945 mL	7.4863 mL
	20 mM	0.2246 mL	1.1229 mL	2.2459 mL	5.6147 mL
	25 mM	0.1797 mL	0.8984 mL	1.7967 mL	4.4918 mL
	30 mM	0.1497 mL	0.7486 mL	1.4973 mL	3.7431 mL
	40 mM	0.1123 mL	0.5615 mL	1.1229 mL	2.8073 mL
	50 mM	0.0898 mL	0.4492 mL	0.8984 mL	2.2459 mL
	60 mM	0.0749 mL	0.3743 mL	0.7486 mL	1.8716 mL
	80 mM	0.0561 mL	0.2807 mL	0.5615 mL	1.4037 mL
	100 mM	0.0449 mL	0.2246 mL	0.4492 mL	1.1229 mL

(RS)-AMPA hydrochloride Related Classifications

Neurological Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(RS)-AMPA2922283-04-1(±)-AMPAiGluRIonotropic glutamate receptorsDepolarizationsmotoneuronesinterneuronesglutamateCNSkainicL-glutamicneurotransmitterNMDAInhibitorinhibitorinhibit

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