(S)-Adenosylmethionine decarboxylated-d₃ (sulfuric) 

(S)-Adenosylmethionine decarboxylated-d₃ (sulfuric) is the deuterium labeled (S)-Adenosylmethionine decarboxylated sulfuric[1].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

C₁₄H₂₁D₃N₆O₇S₂.xHSO₄

22365-13-5

Solid

White to off-white

O[C@H]1[C@](O[C@@H]([C@H]1O)C[S+](C([2H])([2H])[2H])CCCN)([H])N2C3=NC=NC(N)=C3N=C2.O=S(O)([O-])=O.O=S(O)(O)=O.[x]

Room temperature in continental US; may vary elsewhere.

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.  [Content Brief]