2. PROTAC
  3. Ligands for E3 Ligase
  4. (S)-Deoxy-thalidomide

(S)-Deoxy-thalidomide is an E3 ubiquitin ligase ligand. (S)-Deoxy-thalidomide can be linked to the target protein ligand through a linker to form PROTAC K-Ras Degrader-3 (HY-168054). PROTAC K-Ras Degrader-3 can target KRAS mutant proteins for degradation.

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(S)-Deoxy-thalidomide Chemical Structure

(S)-Deoxy-thalidomide Chemical Structure

CAS No. : 107657-57-8

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(S)-Deoxy-thalidomide Related Antibodies

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Description

(S)-Deoxy-thalidomide is an E3 ubiquitin ligase ligand. (S)-Deoxy-thalidomide can be linked to the target protein ligand through a linker to form PROTAC K-Ras Degrader-3 (HY-168054). PROTAC K-Ras Degrader-3 can target KRAS mutant proteins for degradation[1].

Molecular Weight

244.25

Formula

C13H12N2O3
CAS No.
SMILES

O=C(CC1)NC([C@H]1N2C(C3=CC=CC=C3C2)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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(S)-Deoxy-thalidomide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S)-Deoxy-thalidomide107657-57-8Ligands for E3 LigaseE3 ligase-recruiting MoietyInhibitorinhibitorinhibit

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