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  3. Biochemical Assay Reagents
  4. (S)-p-SCN-Bn-DOTA

(S)-p-SCN-Bn-DOTAis a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. (S)-p-SCN-Bn-DOTA can be used for conjugation of peptides and radionuclides.

For research use only. We do not sell to patients.

(S)-p-SCN-Bn-DOTA Chemical Structure

(S)-p-SCN-Bn-DOTA Chemical Structure

CAS No. : 1020407-41-3

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Based on 1 publication(s) in Google Scholar

Other Forms of (S)-p-SCN-Bn-DOTA:

(S)-p-SCN-Bn-DOTA Related Antibodies

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Description

(S)-p-SCN-Bn-DOTAis a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. (S)-p-SCN-Bn-DOTA can be used for conjugation of peptides and radionuclides.

Molecular Weight

551.61

Formula

C24H33N5O8S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC(CN(CCN(CCN(CCN(C1)CC(O)=O)CC(O)=O)CC(O)=O)[C@H]1CC2=CC=C(C=C2)N=C=S)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (226.61 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8129 mL 9.0644 mL 18.1287 mL
5 mM 0.3626 mL 1.8129 mL 3.6258 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.8129 mL 9.0644 mL 18.1288 mL 45.3219 mL
5 mM 0.3626 mL 1.8129 mL 3.6258 mL 9.0644 mL
10 mM 0.1813 mL 0.9064 mL 1.8129 mL 4.5322 mL
15 mM 0.1209 mL 0.6043 mL 1.2086 mL 3.0215 mL
20 mM 0.0906 mL 0.4532 mL 0.9064 mL 2.2661 mL
25 mM 0.0725 mL 0.3626 mL 0.7252 mL 1.8129 mL
30 mM 0.0604 mL 0.3021 mL 0.6043 mL 1.5107 mL
40 mM 0.0453 mL 0.2266 mL 0.4532 mL 1.1330 mL
50 mM 0.0363 mL 0.1813 mL 0.3626 mL 0.9064 mL
60 mM 0.0302 mL 0.1511 mL 0.3021 mL 0.7554 mL
80 mM 0.0227 mL 0.1133 mL 0.2266 mL 0.5665 mL
100 mM 0.0181 mL 0.0906 mL 0.1813 mL 0.4532 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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(S)-p-SCN-Bn-DOTA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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(S)-p-SCN-Bn-DOTA1020407-41-3Biochemical Assay ReagentsInhibitorinhibitorinhibit

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