2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. (S,R,S)-AHPC-C4-NH2 dihydrochloride

(S,R,S)-AHPC-C4-NH2 dihydrochloride  (Synonyms: VH032-C4-NH2 dihydrochloride)

Cat. No.: HY-114176B
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(S,R,S)-AHPC-C4-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC.

For research use only. We do not sell to patients.

(S,R,S)-AHPC-C4-NH2 dihydrochloride Chemical Structure

(S,R,S)-AHPC-C4-NH2 dihydrochloride Chemical Structure

CAS No. : 2341796-78-7

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Based on 1 publication(s) in Google Scholar

Other Forms of (S,R,S)-AHPC-C4-NH2 dihydrochloride:

(S,R,S)-AHPC-C4-NH2 dihydrochloride Related Antibodies

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor

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Description

(S,R,S)-AHPC-C4-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC[1].

IC50 & Target

VHL

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(S,R,S)-AHPC-C4-NH2 dihydrochloride Related Antibodies
Molecular Weight

602.62

Formula

C27H41Cl2N5O4S
CAS No.
Appearance

Solid

Color

Light yellow to green yellow

SMILES

O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(CCCCN)=O)=O)C[C@H](O)C3.Cl.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation
References
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(S,R,S)-AHPC-C4-NH2 dihydrochloride Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S,R,S)-AHPC-C4-NH22341796-78-7VH032-C4-NH2E3 Ligase Ligand-Linker ConjugatesInhibitorinhibitorinhibit

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(S,R,S)-AHPC-C4-NH2 dihydrochloride
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