(S)-Thioctic acid (Synonyms: (S)-lipoic acid; (S)-5-(1,2-Dithiolan-3-yl)pentanoic acid)

Cat. No.: HY-W014590 Purity: 99.74%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

(S)-Thioctic acid ((S)-lipoic acid; (S)-5-(1,2-Dithiolan-3-yl)pentanoic acid) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

(S)-Thioctic acid Chemical Structure

CAS No. : 1077-27-6

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Description

(S)-Thioctic acid ((S)-lipoic acid; (S)-5-(1,2-Dithiolan-3-yl)pentanoic acid) is a biochemical reagent that can be used as a biological material or organic compound for life science related research^[1].

Molecular Weight

206.33

Formula

C₈H₁₄O₂S₂

CAS No.

1077-27-6

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(O)CCCC[C@@H]1SSCC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 200 mg/mL (969.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.8466 mL	24.2330 mL	48.4660 mL
5 mM	0.9693 mL	4.8466 mL	9.6932 mL
10 mM	0.4847 mL	2.4233 mL	4.8466 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.74%

Select Batch:

Data Sheet (265 KB) SDS (393 KB)

COA (244 KB) HNMR (252 KB) LCMS (88 KB)

Handling Instructions (2659 KB)

References

[1]. Bergmeyer H U, et al. Biochemical reagents[M]//Methods of Enzymatic Analysis. Academic Press, 1965: 967-1037.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.8466 mL	24.2330 mL	48.4660 mL	121.1651 mL
	5 mM	0.9693 mL	4.8466 mL	9.6932 mL	24.2330 mL
	10 mM	0.4847 mL	2.4233 mL	4.8466 mL	12.1165 mL
	15 mM	0.3231 mL	1.6155 mL	3.2311 mL	8.0777 mL
	20 mM	0.2423 mL	1.2117 mL	2.4233 mL	6.0583 mL
	25 mM	0.1939 mL	0.9693 mL	1.9386 mL	4.8466 mL
	30 mM	0.1616 mL	0.8078 mL	1.6155 mL	4.0388 mL
	40 mM	0.1212 mL	0.6058 mL	1.2117 mL	3.0291 mL
	50 mM	0.0969 mL	0.4847 mL	0.9693 mL	2.4233 mL
	60 mM	0.0808 mL	0.4039 mL	0.8078 mL	2.0194 mL
	80 mM	0.0606 mL	0.3029 mL	0.6058 mL	1.5146 mL
	100 mM	0.0485 mL	0.2423 mL	0.4847 mL	1.2117 mL

(S)-Thioctic acid Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S)-Thioctic acid1077-27-6(S)-lipoic acid (S)-5-(1,2-Dithiolan-3-yl)pentanoic acidOthersbiochemical reagentbiological materialorganic compoundlife scienceInhibitorinhibitorinhibit

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