2. Vitamin D Related/Nuclear Receptor
  3. Constitutive Androstane Receptor
  4. S07662

S07662 is a human constitutive androstane receptor (hCAR) inhibitor with an IC50 of 0.7 μM. S07662 recruits the corepressor NCoR in cell-based assays and attenuate the expression of CYP2B6 mRNA in human primary hepatocytes induced by phenytoin (HY-B0448) and CITCO (HY-103244).

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S07662 Chemical Structure

S07662 Chemical Structure

CAS No. : 883226-64-0

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S07662 Related Antibodies

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Description

S07662 is a human constitutive androstane receptor (hCAR) inhibitor with an IC50 of 0.7 μM. S07662 recruits the corepressor NCoR in cell-based assays and attenuate the expression of CYP2B6 mRNA in human primary hepatocytes induced by phenytoin (HY-B0448) and CITCO (HY-103244)[1].

IC50 & Target

IC50: 0.7 μM (hCAR)[1].
Molecular Weight

300.38

Formula

C16H16N2O2S
CAS No.
SMILES

O=C(NCC1=C(C)OC2=C1C=CC=C2)NCC3=CC=CS3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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S07662 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

S07662883226-64-0S 07662S-07662Constitutive Androstane ReceptorCARNR1I3CYP2B6 mRNACITCOHuman primary hepatocytes,Inhibitorinhibitorinhibit

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HY-110134
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