SAAP 148 TFA

Cat. No.: HY-P10233A Purity: 99.72%: FAQs
Data Sheet SDS COA Handling Instructions

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SAAP 148 TFA is an antimicrobial and antibiofilm agent, and exhibits inhibitory efficacy against antibiotic-resistant pathogens, with LC₅₀ of 0.8-12.8 μM.

For research use only. We do not sell to patients.

SAAP 148 TFA Chemical Structure

Size	Price	Stock	Quantity
1 mg	USD 75	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 170	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Other Forms of SAAP 148 TFA:

SAAP 148 Get quote

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Biological Activity
Purity & Documentation
References
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Description

SAAP 148 TFA is an antimicrobial and antibiofilm agent, and exhibits inhibitory efficacy against antibiotic-resistant pathogens, with LC₅₀ of 0.8-12.8 μM^[1].

Molecular Weight

3267.06 (free base)

Formula

C₁₅₇H₂₆₁N₄₉O₂₇.xC₂HF₃O₂

Appearance

Solid

Color

White to off-white

Sequence

Ac-Leu-Lys-Arg-Val-Trp-Lys-Arg-Val-Phe-Lys-Leu-Leu-Lys-Arg-Tyr-Trp-Arg-Gln-Leu-Lys-Lys-Pro-Val-Arg-NH2

Sequence Shortening

Ac-LKRVWKRVFKLLKRYWRQLKKPVR-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 48 mg/mL (Need ultrasonic and warming)

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.72%

Select Batch:

Data Sheet (275 KB) SDS (252 KB)

COA (259 KB) RP-HPLC (112 KB) MS (259 KB)

Handling Instructions (2659 KB)

References

[1]. de Breij A, et al., The antimicrobial peptide SAAP-148 combats drug-resistant bacteria and biofilms. Sci Transl Med. 2018 Jan 10;10(423):eaan4044. [Content Brief]

SAAP 148 TFA Related Classifications

Infection

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SAAP 148SAAP148SAAP-148BacterialC57BL/6J miceS. aureusP. aeruginosaA. baumanniiInhibitorinhibitorinhibit

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