1. Immunology/Inflammation Apoptosis NF-κB
  2. NO Synthase TNF Receptor NF-κB COX Interleukin Related
  3. Sabialimon P

Sabialimon P (compound 16) is a NO release inhibitor (IC50=18.12 μM) with anti-inflammatory activity. Sabialimon P significantly reduces the secretion of TNF-α, iNOS, IL-6 and NF-κB and inhibits the expression of COX-2 and NF-κB/p65 in RAW264.7 cells induced by LPS (HY-D1056).

For research use only. We do not sell to patients.

Sabialimon P Chemical Structure

Sabialimon P Chemical Structure

CAS No. : 2267333-96-8

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Description

Sabialimon P (compound 16) is a NO release inhibitor (IC50=18.12 μM) with anti-inflammatory activity. Sabialimon P significantly reduces the secretion of TNF-α, iNOS, IL-6 and NF-κB and inhibits the expression of COX-2 and NF-κB/p65 in RAW264.7 cells induced by LPS (HY-D1056)[1].

Molecular Weight

486.73

Formula

C31H50O4

CAS No.
SMILES

COC([C@]12[C@](CC(C)(CC2)C)([H])C3=CC[C@@]([C@@]4([C@@](C(C)([C@H](C[C@@H]4O)O)C)([H])CC5)C)([H])[C@]5(C)[C@@]3(CC1)C)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Sabialimon P
Cat. No.:
HY-159516
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