Sar-[D-Phe8]-des-Arg9-Bradykinin

Cat. No.: HY-103291 Purity: 99.34%: FAQs
Data Sheet SDS COA Handling Instructions

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Sar-[D-Phe8]-des-Arg9-Bradykinin is a agonist of B1 receptor. Sar-[D-Phe8]-des-Arg9-Bradykinin selectively amplifies the contractile response when incubation with human recombinant interleukin-1 β (IL-1 β) in rabbit aortic rings.

For research use only. We do not sell to patients.

Sar-[D-Phe8]-des-Arg9-Bradykinin Chemical Structure

CAS No. : 126959-88-4

Size	Price	Stock	Quantity
5 mg	USD 96	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 155	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 265	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 370	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 510	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

975.10

Formula

C₄₇H₆₆N₁₂O₁₁

CAS No.

126959-88-4

Appearance

Solid

Color

White to off-white

Sequence

{Sar}-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe

Sequence Shortening

{Sar}-RPPGFSPF

SMILES

O=C([C@H]1N(CCC1)C([C@H](CCCNC(N)=N)NC(CNC)=O)=O)N2[C@@H](CCC2)C(NCC(N[C@H](C(N[C@@H](CO)C(N3[C@@H](CCC3)C(N[C@@H](C(O)=O)CC4=CC=CC=C4)=O)=O)=O)CC5=CC=CC=C5)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (102.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.0255 mL	5.1277 mL	10.2554 mL
5 mM	0.2051 mL	1.0255 mL	2.0511 mL
10 mM	0.1026 mL	0.5128 mL	1.0255 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.34%

Select Batch:

Data Sheet (271 KB) SDS (252 KB)

COA (248 KB) RP-HPLC (112 KB) MS (204 KB)

Handling Instructions (2659 KB)

References

[1]. Levesque L, et al. Regulation of kinin-induced contraction and DNA synthesis by inflammatory cytokines in the smooth muscle of the rabbit aorta. Br J Pharmacol. 1995 Sep;116(1):1673-9. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.0255 mL	5.1277 mL	10.2554 mL	25.6384 mL
	5 mM	0.2051 mL	1.0255 mL	2.0511 mL	5.1277 mL
	10 mM	0.1026 mL	0.5128 mL	1.0255 mL	2.5638 mL
	15 mM	0.0684 mL	0.3418 mL	0.6837 mL	1.7092 mL
	20 mM	0.0513 mL	0.2564 mL	0.5128 mL	1.2819 mL
	25 mM	0.0410 mL	0.2051 mL	0.4102 mL	1.0255 mL
	30 mM	0.0342 mL	0.1709 mL	0.3418 mL	0.8546 mL
	40 mM	0.0256 mL	0.1282 mL	0.2564 mL	0.6410 mL
	50 mM	0.0205 mL	0.1026 mL	0.2051 mL	0.5128 mL
	60 mM	0.0171 mL	0.0855 mL	0.1709 mL	0.4273 mL
	80 mM	0.0128 mL	0.0641 mL	0.1282 mL	0.3205 mL
	100 mM	0.0103 mL	0.0513 mL	0.1026 mL	0.2564 mL