2. GPCR/G Protein
  3. Endothelin Receptor
  4. Sarafotoxin S6a TFA

Sarafotoxin S6a TFA , a sarafotoxin analogue, is a endothelin receptor agonist and has an ETA/ETB selectivity profile similar to that of Endothelin-3 (HY-P0204). Sarafotoxin S6a TFA elicits the pig coronary artery with an EC50 value of 7.5 nM.

For research use only. We do not sell to patients.

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Sarafotoxin S6a TFA Chemical Structure

Sarafotoxin S6a TFA Chemical Structure

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Other Forms of Sarafotoxin S6a TFA:

Sarafotoxin S6a TFA Related Antibodies

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Description

Sarafotoxin S6a TFA , a sarafotoxin analogue, is a endothelin receptor agonist and has an ETA/ETB selectivity profile similar to that of Endothelin-3 (HY-P0204). Sarafotoxin S6a TFA elicits the pig coronary artery with an EC50 value of 7.5 nM[1].

IC50 & Target[1]

ETB

 

ETA

 

In Vitro

Sarafotoxin S6a TFA is a rather weak agonist effect in guinea-pig aorta, the eliting concentration (EC50) is 150 nM in guinea-pig aorta.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Sarafotoxin S6a TFA Related Antibodies
Molecular Weight

2514.85 (free acid)

Formula

C105H156N28O34S5.xC2HF3O2
Sequence

Cys-Ser-Cys-Lys-Asp-Met-Thr-Asp-Lys-Glu-Cys-Leu-Asn-Phe-Cys-His-Gln-Asp-Val-Ile-Trp (Disulfide bridge:Cys1-Cys15;Cys3-Cys11)
Sequence Shortening

CSCKDMTDKECLNFCHQDVIW (Disulfide bridge:Cys1-Cys15;Cys3-Cys11)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility

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In Vivo:

The following protocol is derived from the literature and is for reference only. It is recommended to first try a small sample.

  • Protocol 1

    S6a is dissolved in 0.1% aqueous acetic acid and diluted in 0.9% NaCl[1].

In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
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Sarafotoxin S6a TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sarafotoxin S6aEndothelin Receptorguinea-pigaortaendothelin receptorcoronary arteryEndothelin-3Inhibitorinhibitorinhibit

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Sarafotoxin S6a TFA
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