1. Apoptosis
  2. Caspase
  3. Sarglaroids F

Sarglaroids F (compound 6) is an anti-inflammatory agent isolated from the roots of Grass Coral. Sarglaroids F inhibits LPS/ATP-induced IL-1β release by affecting K+ efflux and reducing Caspase-1(P20) levels. Sarglaroids F is not cytotoxic to RAW264.7 cells.

For research use only. We do not sell to patients.

Sarglaroids F Chemical Structure

Sarglaroids F Chemical Structure

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Description

Sarglaroids F (compound 6) is an anti-inflammatory agent isolated from the roots of Grass Coral. Sarglaroids F inhibits LPS/ATP-induced IL-1β release by affecting K+ efflux and reducing Caspase-1(P20) levels. Sarglaroids F is not cytotoxic to RAW264.7 cells[1].

IC50 & Target

Caspase-1[1]

Molecular Weight

692.75

Formula

C38H44O12

SMILES

[H][C@@]1([C@](O)(COC(/C(C)=C/C)=O)[C@H]2C[C@H]2[C@@]1([C@]([C@H]3O)([C@@]4([C@@]5([H])/C(C([C@H](O)[C@@]6(C)[C@H]7[C@H](C7)C3=C65)=O)=C(C)/C(OC)=O)O8)[H])C)CC4=C(COC(C)=O)C8=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Sarglaroids F
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HY-N12235
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