2. Anti-infection
  3. SARS-CoV
  4. SARS-CoV MPro-IN-2

SARS-CoV MPro-IN-2 (compound 15) is a potent inhibitor of SARS-CoV-2 Mpro with an IC50 value of 72.07 nM. The main protease (Mpro) of the virus as the major enzyme processing viral polyproteins contributes to the replication and transcription of SARS-CoV-2 in host cells, and has been characterized as an attractive target in agent discovery. SARS-CoV MPro-IN-2 has the potential for the research of COVID-19.

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SARS-CoV MPro-IN-2 Chemical Structure

SARS-CoV MPro-IN-2 Chemical Structure

CAS No. : 81418-42-0

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SARS-CoV MPro-IN-2 Related Antibodies

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Description

SARS-CoV MPro-IN-2 (compound 15) is a potent inhibitor of SARS-CoV-2 Mpro with an IC50 value of 72.07 nM. The main protease (Mpro) of the virus as the major enzyme processing viral polyproteins contributes to the replication and transcription of SARS-CoV-2 in host cells, and has been characterized as an attractive target in agent discovery. SARS-CoV MPro-IN-2 has the potential for the research of COVID-19[1].

Molecular Weight

230.22

Formula

C13H10O4
CAS No.
SMILES

O=C1C(C(C)=O)=CC(C2=C1C(OC)=CC=C2)=O
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SARS-CoV MPro-IN-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SARS-CoV MPro-IN-281418-42-0SARS-CoVSARS coronavirusSARS-CoV-2 MproRNACOVID-19replicationtranscriptionattractive targetdrug discoveryInhibitorinhibitorinhibit

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