2. GPCR/G Protein
  3. Urotensin Receptor
  4. SB-611812

SB-611812 is a urotensin II receptor (UTR) antagonist with the potential in the research of cardiovascular disease.

For research use only. We do not sell to patients.

SB-611812 Chemical Structure

SB-611812 Chemical Structure

CAS No. : 345892-71-9

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1 mg USD 80 In-stock
5 mg USD 160 In-stock
10 mg USD 256 In-stock
25 mg USD 512 In-stock
50 mg USD 820 In-stock
100 mg USD 1310 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

SB-611812 is a urotensin II receptor (UTR) antagonist with the potential in the research of cardiovascular disease[1][2].

Molecular Weight

491.74

Formula

C17H16Cl3F3N2O3S
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=S(NC1=CC=C(C(OCCN(C)C)=C1)Cl)(C2=C(C=C(C(F)(F)F)C=C2Cl)Cl)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 16.67 mg/mL (33.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0336 mL 10.1680 mL 20.3360 mL
5 mM 0.4067 mL 2.0336 mL 4.0672 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0336 mL 10.1680 mL 20.3360 mL 50.8399 mL
5 mM 0.4067 mL 2.0336 mL 4.0672 mL 10.1680 mL
10 mM 0.2034 mL 1.0168 mL 2.0336 mL 5.0840 mL
15 mM 0.1356 mL 0.6779 mL 1.3557 mL 3.3893 mL
20 mM 0.1017 mL 0.5084 mL 1.0168 mL 2.5420 mL
25 mM 0.0813 mL 0.4067 mL 0.8134 mL 2.0336 mL
30 mM 0.0678 mL 0.3389 mL 0.6779 mL 1.6947 mL
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SB-611812 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SB-611812345892-71-9SB611812SB 611812Urotensin ReceptorUT receptorInhibitorinhibitorinhibit

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