2. GPCR/G Protein Immunology/Inflammation
  3. CCR
  4. SB-649701

SB-649701 is a potent human CCR8 antagonist, with a pIC50 of 7.7. AZ084 can be used for the research of asthma.

For research use only. We do not sell to patients.

SB-649701 Chemical Structure

SB-649701 Chemical Structure

CAS No. : 935262-95-6

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SB-649701 Related Antibodies

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CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9

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Description

SB-649701 is a potent human CCR8 antagonist, with a pIC50 of 7.7. AZ084 can be used for the research of asthma[1].

IC50 & Target[1]

CCR8

7.7 (pIC50)

Molecular Weight

456.54

Formula

C27H28N4O3
CAS No.
SMILES

COC1=CC2=C(C=C1)N=CC=C2[C@@H]3CN(C4CCN(CC4)CC5=CC6=CC=CC=C6N5)C(O3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SB-649701 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SB-649701935262-95-6SB649701SB 649701CCRCC chemokine receptorInhibitorinhibitorinhibit

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