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IGL

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  • HY-P72438
    TREM-2 Protein, Cynomolgus (HEK293, His)

    Ig-like domain-containing protein; TREM2; Triggering receptor expressed on myeloid cells 2

    		 Cynomolgus HEK293
    TREM-2 protein forms a signaling complex with TYROBP, activates cells upon ligand binding, and acts as a receptor for amyloid beta, lipoproteins, and apolipoproteins. It promotes their uptake by microglia, triggering activation, proliferation, migration, apoptosis and cytokine expression. TREM-2 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived TREM-2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TREM-2 Protein, Cynomolgus (HEK293, His) is 156 a.a., with molecular weight of 28-40 kDa.
  • HY-P70743
    Siglec-15 Protein, Cynomolgus (HEK293, His)

    Sialic acid-binding Ig-like lectin 15; SIGLec-15; CD33 antigen-like 3; CD33L3

    		 Cynomolgus HEK293
    Siglec-15 Protein, a Siglec family member and type-1 transmembrane protein, is constitutively expressed in osteoclasts, macrophages and dendritic cells. Siglec-15 plays a pivotal role in the development and differentiation of osteoclastogenesis, inhibiting antigen-specific T cell responses in vitro and in vivo. Siglec-15 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Siglec-15 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Siglec-15 Protein, Cynomolgus (HEK293, His) is 244 a.a., with molecular weight of 30-40 kDa.
  • HY-P70960
    Siglec-5 Protein, Cynomolgus (HEK293, His)

    Sialic acid-binding Ig-like lectin 5; SIGLec-5

    		 Cynomolgus HEK293
    Siglec-5 Protein is a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. Siglec-5 is a member of the CD33-related subset of Siglecs and is expressed on myeloid cells of the hemopoietic system. Siglec-5 inhibits the response of innate immune cells, such as monocytes and neutrophils against pathogens. Siglec-5 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Siglec-5 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Siglec-5 Protein, Cynomolgus (HEK293, His) is 419 a.a., with molecular weight of ~90.0 kDa.

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