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Antxr2

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  • HY-P76151
    CMG-2/ANTXR2 Protein, Human (HEK293, Fc)

    Anthrax toxin receptor 2; Capillary morphogenesis gene 2 protein; CMG-2; Antxr2

    		 Human HEK293
    CMG-2/ANTXR2 is essential for cellular interactions with laminin and the extracellular matrix. As a receptor for the protective antigen (PA) of B. anthracis, it undergoes heptamerization upon PA binding. The complex is internalized through a clathrin-dependent pathway, and in the endosomal membrane (pH < 7), it rearranges to form a pore, facilitating the entry of other components of anthrax toxin into the cytoplasm. CMG-2/ANTXR2 Protein, Human (HEK293, Fc) is the recombinant human-derived CMG-2/ANTXR2 protein, expressed by HEK293 , with C-hFc labeled tag.
  • HY-P700656
    CMG-2/ANTXR2 Protein, Human (HEK293, His)

    Antxr2; HFS; cI-35; CMG-2; CMG2; ISH; JHF; JHS

    		 Human HEK293
    The CMG-2/ANTXR2 protein, acting as a receptor for anthrax toxin, binds to collagen IV and laminin, suggesting its role in extracellular matrix adhesion. Gene mutations are associated with juvenile hyaline fibromatosis and infantile systemic hyalinosis. Multiple isoforms have been found. It is expressed in various tissues, including the prostate and endometrium. CMG-2/ANTXR2 Protein, Human (HEK293, His) is the recombinant human-derived CMG-2/ANTXR2 protein, expressed by HEK293 , with C-His labeled tag.

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