2. Search Result
Search Result
Results for "

Fzd2

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Compare Product Name Species Source
  • HY-P78722
    FZD2 Protein, Human (HEK293, Fc)

    Fzd2; Frizzled-2; Fz-2; hFz2; FzE2

    		 Human HEK293
    FZD2 Protein, a receptor for Wnt proteins, activates the beta-catenin canonical pathway, inhibiting GSK-3 kinase and triggering Wnt target genes. FZD2 and some family members have a secondary PKC-calcium pathway, yet its integration with the canonical pathway remains unclear. PKC seems crucial for Wnt-mediated GSK-3 kinase inactivation. These pathways may involve G-protein interactions, contributing to polarity information transmission during tissue morphogenesis. Notably, FZD2 acts as a receptor for C. difficile toxin TcdB in the colonic epithelium, occupying the Wnt-adducted palmitoleate binding site, preventing downstream Wnt signaling. FZD2 Protein, Human (HEK293, Fc) is the recombinant human-derived FZD2 protein, expressed by HEK293, with C-hFc labeled tag. The total length of FZD2 Protein, Human (HEK293, Fc) is 167 a.a., with molecular weight of 50-62 kDa.

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: