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Ifnl2

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  • HY-P72553
    IFN-lambda 2/IL-28A Protein, Human (HEK293, His)

    Interferon lambda-2; IFN-lambda-2; IL-28A; Ifnl2; IL28A; ZCYTO20

    		 Human HEK293
    IFN-lambda 2 (IL-28A) is a member of the Type-III interferon family. IFN-lambda 2 has antiviral antitumour and immunomodulatory activities. IFN-lambda 2 signals through a heterodimeric receptor complex comprising IFNLR1 and IL-10RB. When binding to the receptor complex, Jak1 and Tyk2 will be activated, and leads to tyrosine phosphorylation of the IFN-λR1 and activation of STAT1 and STAT2. Activated STAT1 and STAT2 together with IRF-9 form a trimeric transcription factor complex (ISGF3). The formed ISGF3 then translocate to the nucleus and promotes the production of IFN-stimulated genes (ISGs). IFN-lambda 2/IL-28A Protein, Human (HEK293, His) is a recombinant human IFN-lambda 2 (V26-V200) with C-terminal 6*His tag, which is expressed in HEK293.
  • HY-P700119AF
    Animal-Free IFN-lambda 2/IL-28A Protein, Human (His)

    Interferon lambda-2; IFN-lambda-2; IL-28A; Ifnl2; IL28A; ZCYTO20

    		 Human E. coli
    IFN-lambda 2/IL-28A protein is a multifunctional cytokine with antiviral, antitumor, and immunomodulatory activities. It plays a key role in antiviral host defense, particularly within epithelial tissues. Animal-Free IFN-lambda 2/IL-28A Protein, Human (His) is the recombinant human-derived animal-FreeIFN-lambda 2/IL-28A protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IFN-lambda 2/IL-28A Protein, Human (His) is 174 a.a., with molecular weight of ~20.60 kDa.
  • HY-P77005
    IFN-lambda 2/IL-28A Protein, Human (P.pastoris, His)

    Interferon lambda-2; IFN-lambda-2; IL-28A; Ifnl2; IL28A; ZCYTO20

    		 Human P. pastoris
    IFN-lambda 2 (IL-28A) is a member of the Type-III interferon family. IFN-lambda 2 has antiviral antitumour and immunomodulatory activities. IFN-lambda 2 signals through a heterodimeric receptor complex comprising IFNLR1 and IL-10RB. When binding to the receptor complex, Jak1 and Tyk2 will be activated, and leads to tyrosine phosphorylation of the IFN-λR1 and activation of STAT1 and STAT2. Activated STAT1 and STAT2 together with IRF-9 form a trimeric transcription factor complex (ISGF3). The formed ISGF3 then translocate to the nucleus and promotes the production of IFN-stimulated genes (ISGs). IFN-lambda 2/IL-28A Protein, Human (P.pastoris, His) is a recombinant human IFN-lambda 2 (V26-V200) with C-terminal His tag, which is expressed in P.pastoris.

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