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Mertk

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  • HY-P73824
    Mer Protein, Human (HEK293)

    Tyrosine-protein kinase Mer; Mertk; MER

    		 Human HEK293
    Mer protein is a receptor tyrosine kinase that transduces signals by binding to ligands such as LGALS3, TUB, TULP1, or GAS6, regulating cell survival, migration, differentiation, and apoptotic cell phagocytosis (endocytosis). Ligand binding induces autophosphorylation of MERTK, creating a docking site for downstream molecules. Mer Protein, Human (HEK293) is the recombinant human-derived Mer protein, expressed by HEK293 , with tag free. The total length of Mer Protein, Human (HEK293) is 479 a.a., with molecular weight of 110-120 kDa.
  • HY-P70958
    Mer Protein, Human (HEK293, His)

    Tyrosine-protein kinase Mer/Proto-oncogene c-Mer/Receptor tyrosine kinase Mertk/Mertk/MER

    		 Human HEK293
    MER tyrosine kinase (MERTK) is a transmembrane protein with transmembrane receptor protein tyrosine kinase activity. MERTK has oncogenic properties and is often overexpressed or activated in various malignancies, activating several downstream signaling pathways including MAPK/ERK, PI3K/AKT, and JAK/STAT. MERTK is involved in animal organ development, synapse elimination, neutrophil clearance and protein kinase B signaling. Mer Protein, Human (HEK293, His) is the recombinant human-derived Mer protein, expressed by HEK293, with C-6*His labeled tag. The total length of Mer Protein, Human (HEK293, His) is 323 a.a., with molecular weight of 60-120 kDa.
  • HY-P700442
    MERTK Protein, Human (HEK293, His)

    Mertk; c-mer proto-oncogene tyrosine kinase; tyrosine-protein kinase Mer; mer; RP38; STK kinase; proto-oncogene c-Mer; MER receptor tyrosine kinase; receptor tyrosine kinase Mertk; MER; c-mer; MGC133349

    		 Human HEK293
    Mer protein is a receptor tyrosine kinase that transduces signals by binding to ligands such as LGALS3, TUB, TULP1, or GAS6, regulating cell survival, migration, differentiation, and apoptotic cell phagocytosis (endocytosis). Ligand binding induces autophosphorylation of MERTK, creating a docking site for downstream molecules. MERTK Protein, Human (HEK293, His) is the recombinant human-derived MERTK protein, expressed by HEK293 , with C-10*His labeled tag. The total length of MERTK Protein, Human (HEK293, His) is 485 a.a., with molecular weight of 55.4 kDa.
  • HY-P702704
    MERTK Protein, Human (Biotinylated, sf9, Flag, Avi)

    Mertk; c-mer proto-oncogene tyrosine kinase; tyrosine-protein kinase Mer; mer; RP38; STK kinase; proto-oncogene c-Mer; MER receptor tyrosine kinase; receptor tyrosine kinase Mertk; MER; c-mer; MGC133349

    		 Human Sf9 insect cells
    Mer protein is a receptor tyrosine kinase that transduces signals by binding to ligands such as LGALS3, TUB, TULP1, or GAS6, regulating cell survival, migration, differentiation, and apoptotic cell phagocytosis (endocytosis). Ligand binding induces autophosphorylation of MERTK, creating a docking site for downstream molecules. MERTK Protein, Human (Biotinylated, sf9, Flag, Avi) is the recombinant human-derived MERTK, expressed by Sf9 insect cells , with Avi, Flag labeled tag. ,
  • HY-P73822
    Mer Protein, Human (sf9)

    Tyrosine-protein kinase Mer; Mertk; MER

    		 Human Sf9 insect cells
    Mer protein is a receptor tyrosine kinase that transduces signals by binding to ligands such as LGALS3, TUB, TULP1, or GAS6, regulating cell survival, migration, differentiation, and apoptotic cell phagocytosis (endocytosis). Ligand binding induces autophosphorylation of MERTK, creating a docking site for downstream molecules. Mer Protein, Human (sf9) is the recombinant human-derived Mer protein, expressed by Sf9 insect cells , with tag free. The total length of Mer Protein, Human (sf9) is 295 a.a., with molecular weight of ~29 kDa.
  • HY-P73821
    Mer Protein, Human (sf9, His-GST)

    Tyrosine-protein kinase Mer; Mertk; MER

    		 Human Sf9 insect cells
    Mer protein is a receptor tyrosine kinase that transduces signals by binding to ligands such as LGALS3, TUB, TULP1, or GAS6, regulating cell survival, migration, differentiation, and apoptotic cell phagocytosis (endocytosis). Ligand binding induces autophosphorylation of MERTK, creating a docking site for downstream molecules. Mer Protein, Human (sf9, His-GST) is the recombinant human-derived Mer protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of Mer Protein, Human (sf9, His-GST) is 295 a.a., with molecular weight of ~50 kDa.
  • HY-P73823
    Mer Protein, Human (HEK293, His-Fc)

    Tyrosine-protein kinase Mer; Mertk; MER

    		 Human HEK293
    Mer protein is a receptor tyrosine kinase that transduces signals by binding to ligands such as LGALS3, TUB, TULP1, or GAS6, regulating cell survival, migration, differentiation, and apoptotic cell phagocytosis (endocytosis). Ligand binding induces autophosphorylation of MERTK, creating a docking site for downstream molecules. Mer Protein, Human (HEK293, His-Fc) is the recombinant human-derived Mer protein, expressed by HEK293 , with C-hFc, C-His labeled tag. The total length of Mer Protein, Human (HEK293, His-Fc) is 479 a.a., with molecular weight of 140-150 kDa.
  • HY-P78489
    Mer Protein, Human (HEK293, mFc)

    Mertk; MER; c-Eyk; MGC133349; c-mer; RP38; Tyro12

    		 Human HEK293
    Mer Protein, a receptor tyrosine kinase, transduces signals by binding ligands like LGALS3, TUB, TULP1, or GAS6, regulating cell survival, migration, differentiation, and apoptotic cell phagocytosis (efferocytosis). Ligand binding induces MERTK autophosphorylation, creating docking sites for downstream molecules. Activated by ligand, Mer interacts with GRB2 or PLCG2, inducing MAPK1, MAPK2, FAK/PTK2, or RAC1 phosphorylation. MERTK signaling is implicated in macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization, and engulfment. In the retinal pigment epithelium (RPE), Mer regulates phagocytosis of rod outer segment fragments. Moreover, Mer inhibits Toll-like receptors (TLRs)-mediated innate immune responses by activating STAT1, inducing SOCS1 and SOCS3 production. Mer Protein, Human (HEK293, mFc) is the recombinant human-derived Mer protein, expressed by HEK293, with C-mFc labeled tag. The total length of Mer Protein, Human (HEK293, mFc) is 485 a.a., with molecular weight of 115-140 kDa.

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