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CD163

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Recombinant Proteins Recommended:
Cat. No. Compare Product Name Species Source
  • HY-P700669
    CD163 Protein, Mouse (HEK293, His)

    M130; CD163 molecule; CD163; GHI/61; HbSR; MM130; RM3/1; SCARI1; sCD163

    		 Mouse HEK293
    CD163 protein is pivotal in macrophages for clearing and endocytosing hemoglobin/haptoglobin complexes, safeguarding tissues from oxidative damage. It contributes to iron recycling by facilitating complex endocytosis and heme breakdown, with calcium and pH influencing hemoglobin binding. This initiates intracellular signals involving tyrosine kinase, calcium mobilization, and cytokine secretion. The soluble form, sCD163, released through shedding, may have an anti-inflammatory role. CD163 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD163 protein, expressed by HEK293, with C-His labeled tag. The total length of CD163 Protein, Mouse (HEK293, His) is 1007 a.a., with molecular weight of 120-150 kDa.

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