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MKRN3

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Cat. No. Compare Product Name Species Source
  • HY-P74438
    14-3-3 sigma Protein, Mouse

    14-3-3 protein sigma; HME1; SFN; Stratifin; MKRN3

    		 Mouse E. coli
    14-3-3 sigma protein, an adapter in diverse signaling pathways, binds phosphoserine or phosphothreonine motifs, modulating partner activity. It regulates protein synthesis and cell growth via Akt/mTOR pathway stimulation when bound to KRT17. It may also regulate MDM2 autoubiquitination, activating p53/TP53. Existing as a homodimer, it interacts with GAB2, KRT17, SAMSN1, SRPK2, COPS6, COP1 (for degradation), phosphorylated DAPK2, PI4KB, SLITRK1, and LRRK2 (phosphorylation-dependent). Complexes include XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, and VPS35. 14-3-3 sigma Protein, Mouse is the recombinant mouse-derived 14-3-3 sigma protein, expressed by E. coli, with tag free. The total length of 14-3-3 sigma Protein, Mouse is 248 a.a., with molecular weight of ~32 kDa.

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