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SMPD1

" in MedChemExpress (MCE) Product Catalog:
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  • HY-P76134

    Sphingomyelin phosphodiesterase; Acid sphingomyelinase; ASMase; SMPD1; Asm

    Mouse Sf9 insect cells
    The SMPD1 protein converts sphingomyelin to ceramide through two enzymatic forms, one targeted to endolysosomes and the other released extracellularly.Lysosomal exocytosis becomes a significant source of the secretory form during stress responses.SMPD1 also exports cholesterol from intraendolysosomal membranes and exhibits phospholipase C activities.Its role in stress-induced apoptosis modulation is mediated through ceramide production.SMPD1 Protein, Mouse (sf9, His) is the recombinant mouse-derived SMPD1 protein, expressed by Sf9 insect cells , with C-His labeled tag.

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