Search Result

Search Result

Results for "

(-)-Ingenol

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Complement System (1) Drug Derivative (1) Drug Metabolite (1) HIV (3) PKC (5)
By Research Areas:	Cancer (5) Infection (1) Inflammation/Immunology (4)

15

Inhibitors & Agonists

13

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*Ingenol* (-)-Ingenol	PKC	Cancer
Ingenol is a PKC activator, with a K_i of 30 μM, with antitumor activity.

Ingenol-5,20-acetonide	Others	Others
Ingenol-5,20-acetonide is a natural compound.

Ingenol-3,4,5,20-diacetonide Ingenol 3,4:5,20-bisacetonide	Others	Others
Ingenol-3,4,5,20-diacetonide is a natural compound.

Ingenol-5,20-acetonide-3-O-angelate Ingenol 5,20-acetonide 3-angelate; Ingenol 3-angelate 5,20-acetonide	Others	Others
Ingenol-5,20-acetonide-3-O-angelate is a natural compound.

Ingenol 3,20-dibenzoate	PKC Apoptosis	Inflammation/Immunology
Ingenol 3,20-dibenzoate is a potent protein kinase C (PKC) isoform-selective agonist. Ingenol 3,20-dibenzoate induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu from the cytosolic fraction to the particulate fraction and induces morphologically typical apoptosis through de novo synthesis of macromolecules. Ingenol 3,20-dibenzoate increases the IFN-γ production and degranulation by NK cells, especially when NK cells are stimulated by NSCLC cells .

Ingenol-3-palmitate	HIV	Infection
Ingenol-3-palmitate, an ingenane diterpenoid, is a nature product that could be isolated from the roots of Euphorbia ebracteolata. Ingenol-3-palmitate is a potent HIV-1 (HIV) inhibitor with an IC₅₀ value of 4.1 nM .

Ingenol 3-Hexanoate	Drug Derivative HIV	Cancer
Ingenol 3-Hexanoate, an ingenol semi-synthetic derivative, is a potent anticancer agent. Ingenol 3-Hexanoate can be used in research of cancer .

Ingenol 3-monobenzoate Ingenol 3-benzoate	PKC	Others
Ingenol 3-monobenzoate (Ingenol 3-benzoate) is a disgust inducing agent. Ingenol 3-monobenzoate can bind to and activate PKC (K_i=0.14 nM), inhibit the gene expression of phosphoenolpyruvate carboxykinase, thereby inhibiting gluconeogenesis, and increasing blood cortisol levels, producing food aversion .

Ingenol Mebutate (Standard)	PKC	Inflammation/Immunology Cancer
Ingenol Mebutate (Standard) is the analytical standard of Ingenol Mebutate. This product is intended for research and analytical applications. Ingenol Mebutate is an active ingredient in Euphorbia peplus, acts as a potent PKC modulator, with K_is of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity.

Ingenol 20-palmitate	HIV	Cancer
Ingenol 20-palmitate (compound 2) is a diterpene that can be found in Euphorbia lath yris .

Ingenol disoxate LEO 43204	Drug Metabolite	Others
Ingenol disoxate (LEO 43204) is a drug metabolite, that exhibits potential in ameliorating actinic keratosis .

Ingenol Mebutate 3 Publications Verification Ingenol 3-angelate; PEP005	PKC	Inflammation/Immunology Cancer
Ingenol Mebutate is an active ingredient in Euphorbia peplus, acts as a potent PKC modulator, with K_is of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity.

3-O-(2'E,4'Z-Decadienoyl)ingenol	Complement System	Inflammation/Immunology
3-O-(2'E,4'Z-Decadienoyl)ingenol is a natural diterpene that exhibits significant anticomplement activity with an IC₅₀ of 89.5 μM .

3-O-(2'E,4'E-Decadienoyl)-ingenol	Others	Others
3-O-(2'E,4'E-Decadienoyl)-ingenol is a natural diterpenoid that shows cytotoxicity against human normal cell lines L-O2 and GES-1, with IC₅₀s of 8.22 μM and 6.67 μM, respectively .

3-O-(2'E ,4'E-Decadienoyl)-20-O-acetylingenol	Others	Others
3-O-(2'E ,4'E-Decadienoyl)-20-O-acetylingenol is a ingenol-type diterpenoid that contains a 2,4-decadienoyloxy group .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

MedChemExpress Magic Cece

MedChemExpress: Contact Us; About Us; Headquarters; Distributors; Statement on False Report; Careers

Customer Support: Technical Support; Service; Ordering Information; Easy Return; Shipping Rates & Policies; Intellectual Property Promise

Resources: Free Sample; Resources; Molarity Calculator; Dilution Calculator; Terms & Conditions; Reconstitution Calculator; Specific Activity Calculator; DNA/RNA sequence conversion tools

Subscribe to our E-newsletter

Name
Email *

	Sorry, but the email address you supplied was invalid.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.

Copyright © 2013-2025 MedChemExpress. All Rights Reserved.: Site Map Privacy Policy

Join with us