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Results for "

α-CGRP

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CGRP Receptor (11) Isotope-Labeled Compounds (1)
By Research Areas:	Cardiovascular Disease (8) Inflammation/Immunology (2) Metabolic Disease (3) Neurological Disease (5)

Inhibitors & Agonists

Peptides

Isotope-Labeled Compounds

Targets Recommended: CGRP Receptor

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P0203

α-CGRP (mouse, rat) 3 Publications Verification CGRP (83-119), mouse, rat	CGRP Receptor	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
α-CGRP (mouse, rat), a neuropeptide (calcitonin gene-related peptide (CGRP)) mainly expressed in neuromuscular junction, is a potent vasodilator. α-CGRP (mouse, rat) can lead to a fall in blood pressure and an increase in heart rate by peripheral administration, also relax colonie smooth muscle. α-CGRP (mouse, rat) has the potential in cardiovascular, pro-inflammatory, migraine and metabolic studies .

HY-P0203A

α-CGRP (mouse, rat) (TFA) 3 Publications Verification CGRP (83-119), mouse, rat TFA	CGRP Receptor	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
α-CGRP (mouse, rat) TFA, a neuropeptide (calcitonin gene-related peptide (CGRP)) mainly expressed in neuromuscular junction, is a potent vasodilator. α-CGRP (mouse, rat) TFA can lead to a fall in blood pressure and an increase in heart rate by peripheral administration, also relax colonie smooth muscle. α-CGRP (mouse, rat) TFA has the potential in cardiovascular, pro-inflammatory, migraine and metabolic studies .

HY-P1071

α-CGRP(human) 2 Publications Verification Calcitonin gene-related peptide	CGRP Receptor	Cardiovascular Disease
α-CGRP(human) (Calcitonin gene-related peptide) is a regulatory neuropeptide of 37 amino acids. α-CGRP(human) is widely distributed in the central and peripheral nervous system. α-CGRP(human) is a potent vasodilator and has inotropic and chronotropic effects .

HY-P1071A

α-CGRP(human) TFA 2 Publications Verification Calcitonin gene-related peptide TFA	CGRP Receptor	Cardiovascular Disease
α-CGRP(human) (TFA) is a regulatory neuropeptide of 37 amino acids. α-CGRP(human) (TFA) is widely distributed in the central and peripheral nervous system. α-CGRP(human) (TFA) is a potent vasodilator and has inotropic and chronotropic effects .

HY-P1014

HCGRP-(8-37) 2 Publications Verification Human α-CGRP (8-37)	CGRP Receptor	Cardiovascular Disease Metabolic Disease
HCGRP-(8-37) is a human calcitonin gene-related peptide (hCGRP) fragment and also an antagonist of CGRP receptor.

HY-12366

Ubrogepant MK-1602	CGRP Receptor	Cardiovascular Disease Neurological Disease
Ubrogepant (MK-1602) is an orally active and selective antagonist of calcitonin gene-related peptide receptor (CGRP). Ubrogepant has high affinity for *CGRP* receptors in human and rhesus monkeys, and can effectively block the cAMP response stimulated by *α-CGRP*. Ubrogepant can be used in the study of acute migraine .

HY-P4058

Calcitonin gene-related peptide free acid CGRP free acid	CGRP Receptor	Neurological Disease
Calcitonin gene-related peptide (CGRP) free acid is the deamidated form of α-CGRP(human) (HY-P1071). Calcitonin gene-related peptide can be used to study the effect of C-terminal amidation on CGRP .

HY-P2601A

*Tyr-α-CGRP* (human) TFA**	CGRP Receptor	Others
Tyr-α-CGRP (human) TFA is an N-terminally extended human α-CGRP analog. Tyr-α-CGRP (human) TFA can bind to membrane preparations from rat brain and spleen with IC₅₀ values of 0.2 nM and 0.5 nM, respectively, and induce positive chronotropic and inotropic effects in isolated guinea pig right and left atria with EC₅₀ values of 282 nM and 74 nM, respectively. Tyr-α-CGRP (human) TFA also inhibits contractile responses in rat vas deferens with an EC₅₀ value of 1.9 nM .

HY-12366R

Ubrogepant (Standard) MK-1602 (Standard)	CGRP Receptor	Cardiovascular Disease Neurological Disease
Ubrogepant (Standard) is the analytical standard of Ubrogepant. This product is intended for research and analytical applications. Ubrogepant (MK-1602) is an orally active and selective antagonist of calcitonin gene-related peptide receptor (CGRP). Ubrogepant has high affinity for *CGRP* receptors in human and rhesus monkeys, and can effectively block the cAMP response stimulated by *α-CGRP*. Ubrogepant can be used in the study of acute migraine .

HY-12366S

Ubrogepant-d5 MK-1602-d₅	Isotope-Labeled Compounds CGRP Receptor	Cardiovascular Disease Neurological Disease
Ubrogepant-d₅ (MK-1602-d₅) is deuterium labeled Ubrogepant. Ubrogepant (MK-1602) is an orally active and selective antagonist of calcitonin gene-related peptide receptor (CGRP). Ubrogepant has high affinity for *CGRP* receptors in human and rhesus monkeys, and can effectively block the cAMP response stimulated by *α-CGRP*. Ubrogepant can be used in the study of acute migraine .

HY-10301

MK-3207 3 Publications Verification	CGRP Receptor	Neurological Disease
MK-3207 is an orally active, highly selective and species-specific CGRP receptor antagonist (for human CGRP receptor: IC₅₀=0.12 nM; K_i=0.024 nM). MK-3207 can be used for migraine studies .

Cat. No.	Product Name	Target	Research Area

HY-P0203

α-CGRP (mouse, rat) 3 Publications Verification CGRP (83-119), mouse, rat	CGRP Receptor	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
α-CGRP (mouse, rat), a neuropeptide (calcitonin gene-related peptide (CGRP)) mainly expressed in neuromuscular junction, is a potent vasodilator. α-CGRP (mouse, rat) can lead to a fall in blood pressure and an increase in heart rate by peripheral administration, also relax colonie smooth muscle. α-CGRP (mouse, rat) has the potential in cardiovascular, pro-inflammatory, migraine and metabolic studies .

HY-P0203A

α-CGRP (mouse, rat) (TFA) 3 Publications Verification CGRP (83-119), mouse, rat TFA	CGRP Receptor	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
α-CGRP (mouse, rat) TFA, a neuropeptide (calcitonin gene-related peptide (CGRP)) mainly expressed in neuromuscular junction, is a potent vasodilator. α-CGRP (mouse, rat) TFA can lead to a fall in blood pressure and an increase in heart rate by peripheral administration, also relax colonie smooth muscle. α-CGRP (mouse, rat) TFA has the potential in cardiovascular, pro-inflammatory, migraine and metabolic studies .

HY-P1071

α-CGRP(human) 2 Publications Verification Calcitonin gene-related peptide	CGRP Receptor	Cardiovascular Disease
α-CGRP(human) (Calcitonin gene-related peptide) is a regulatory neuropeptide of 37 amino acids. α-CGRP(human) is widely distributed in the central and peripheral nervous system. α-CGRP(human) is a potent vasodilator and has inotropic and chronotropic effects .

HY-P1071A

α-CGRP(human) TFA 2 Publications Verification Calcitonin gene-related peptide TFA	CGRP Receptor	Cardiovascular Disease
α-CGRP(human) (TFA) is a regulatory neuropeptide of 37 amino acids. α-CGRP(human) (TFA) is widely distributed in the central and peripheral nervous system. α-CGRP(human) (TFA) is a potent vasodilator and has inotropic and chronotropic effects .

HY-P1014

HCGRP-(8-37) 2 Publications Verification Human α-CGRP (8-37)	CGRP Receptor	Cardiovascular Disease Metabolic Disease
HCGRP-(8-37) is a human calcitonin gene-related peptide (hCGRP) fragment and also an antagonist of CGRP receptor.

HY-P4058

Calcitonin gene-related peptide free acid CGRP free acid	CGRP Receptor	Neurological Disease
Calcitonin gene-related peptide (CGRP) free acid is the deamidated form of α-CGRP(human) (HY-P1071). Calcitonin gene-related peptide can be used to study the effect of C-terminal amidation on CGRP .

HY-P2601A

*Tyr-α-CGRP* (human) TFA**	CGRP Receptor	Others
Tyr-α-CGRP (human) TFA is an N-terminally extended human α-CGRP analog. Tyr-α-CGRP (human) TFA can bind to membrane preparations from rat brain and spleen with IC₅₀ values of 0.2 nM and 0.5 nM, respectively, and induce positive chronotropic and inotropic effects in isolated guinea pig right and left atria with EC₅₀ values of 282 nM and 74 nM, respectively. Tyr-α-CGRP (human) TFA also inhibits contractile responses in rat vas deferens with an EC₅₀ value of 1.9 nM .

HY-P4714

*(Tyr27)-α-CGRP* (27-37) (canine, mouse, rat)**	Peptides	Others
(Tyr27)-α-CGRP (27-37) (canine, mouse, rat) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4946

*Biotinyl-α-CGRP* (human)**	Peptides	Others
Biotinyl-α-CGRP (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4941

*Biotinyl-α-CGRP* (mouse, rat)**	Peptides	Others
Biotinyl-α-CGRP (mouse, rat) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

Cat. No.	Product Name	Chemical Structure

HY-12366S

Ubrogepant-d5
Ubrogepant-d₅ (MK-1602-d₅) is deuterium labeled Ubrogepant. Ubrogepant (MK-1602) is an orally active and selective antagonist of calcitonin gene-related peptide receptor (CGRP). Ubrogepant has high affinity for *CGRP* receptors in human and rhesus monkeys, and can effectively block the cAMP response stimulated by *α-CGRP*. Ubrogepant can be used in the study of acute migraine .

Ubrogepant-d5

Ubrogepant-d₅ (MK-1602-d₅) is deuterium labeled Ubrogepant. Ubrogepant (MK-1602) is an orally active and selective antagonist of calcitonin gene-related peptide receptor (CGRP). Ubrogepant has high affinity for CGRP receptors in human and rhesus monkeys, and can effectively block the cAMP response stimulated by α-CGRP. Ubrogepant can be used in the study of acute migraine .

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