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α-GalCer

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-102022
    α-Galactosylceramide
    2 Publications Verification

    α-GalCer; KRN7000

    		 Others Inflammation/Immunology Cancer
    α-Galactosylceramide (α-GalCer) is a synthetic glycolipid with antitumorial and immunostimulatory. α-Galactosylceramide is a very potent NKT cell agonist and binds effectively to CD1d. The complex of α-Galactosylceramide plus CD1d binds the NKT cell TCR (T cell antigen receptor) .
    α-Galactosylceramide
  • HY-144120
    αGalCer-RBD

    		SARS-CoV Infection
    αGalCer-RBD is a self-adjuvanting lipoprotein conjugate. αGalCer-RBD induces potent immunity against SARS-CoV-2 and its variants of concern. αGalCer-RBD conjugate induces RBD-specific, cytokine-producing T cell development. αGalCer-RBD has great potential to be an effective COVID-19 vaccine candidate. α-Galactosylceramide (αGalCer) is a potent invariant natural killer T cell (iNKT) agonist . RBD: receptor-binding domain
    αGalCer-RBD
  • HY-159902
    KRN7000 analog 3

    		Interleukin Related Inflammation/Immunology Cancer
    KRN7000 analog 3 (Compound 14),α-GalCer (HY-102022) analogue with 4-phenoxy substitution, is a iNKT agonist. KRN7000 analog 3 induces higher levels of IL-2 cytokine secretion (range: 49.2-62.6 ng/mL) than a-GalCer (44.1 ng/mL) in mNK1.2 cells. KRN7000 analog 3 is promising for research of antitumor agents and vaccine adjuvants .
    KRN7000 analog 3

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