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Results for "

β1 adrenergic receptor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (96) Androgen Receptor (1) Autophagy (7) Bacterial (3) Calcium Channel (2) Endogenous Metabolite (7) Interleukin Related (5) Isotope-Labeled Compounds (9) NADPH Oxidase (2) TNF Receptor (5) VEGFR (5)
By Research Areas:	Cancer (22) Cardiovascular Disease (74) Endocrinology (42) Inflammation/Immunology (14) Metabolic Disease (11) Neurological Disease (20)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Adrenergic Receptor

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-112071

Prenalterol	Adrenergic Receptor	Cardiovascular Disease
Prenalterol is a selective β1-adrenergic receptor agonist. Prenalterol has no effect on gut smooth muscle contractile activity. Prenalterol can be used for researching cardiovascular disease ^[1].

HY-13715A

Norepinephrine hydrochloride 30+ Cited Publications Levarterenol hydrochloride; L-Noradrenaline hydrochloride	Adrenergic Receptor Autophagy Endogenous Metabolite	Cardiovascular Disease Endocrinology Cancer
Norepinephrine (Levarterenol; L-Noradrenaline) hydrochloride is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α₁, α₂, β₁ receptors ^[1] .

HY-13715

Norepinephrine 30+ Cited Publications Levarterenol; L-Noradrenaline	Endogenous Metabolite Adrenergic Receptor Autophagy	Cardiovascular Disease Endocrinology Cancer
Norepinephrine (Levarterenol; L-Noradrenaline) is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α₁, α₂, β₁ receptors ^[1] .

HY-13715B

Norepinephrine bitartrate monohydrate 30+ Cited Publications Levarterenol bitartrate monohydrate; L-Noradrenaline bitartrate monohydrate	Adrenergic Receptor Autophagy Endogenous Metabolite	Cardiovascular Disease Endocrinology Cancer
Norepinephrine (Levarterenol; L-Noradrenaline) bitartrate monohydrate is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α₁, α₂, β₁ receptors ^[1] .

HY-13715C

Norepinephrine tartrate 30+ Cited Publications Levarterenol tartrate; L-Noradrenaline tartrate	Endogenous Metabolite Adrenergic Receptor Autophagy	Cardiovascular Disease Endocrinology Cancer
Norepinephrine (Levarterenol; L-Noradrenaline) tartrate is a potent adrenergic receptor (AR) agonist. Norepinephrine tartrate activates α₁, α₂, β₁ receptors ^[1] .

HY-106720

Amosulalol YM 09538	Adrenergic Receptor	Cardiovascular Disease
Amosulalol (YM 09538) is an orally active and dual inhibitor of α1/β1-Adrenergic Receptor. Amosulalol exhibits antihypertensive activity via α1-Adrenergic Receptor inhibition. Amosulalol decreases reflexogenic increases in heart rate and plasma renin activity (PRA) via β1-Adrenergic Receptor inhibition in spontaneously hypertensive rats (SHR) ^[1].

HY-17497

Acebutolol	Adrenergic Receptor	Cardiovascular Disease
Acebutolol is an orally active β1 adrenergic receptor (β1AR) antagonist. Acebutolol is used for hypertension, angina pectoris and cardiac arrhythmias research ^[1] .

HY-13715BR

Norepinephrine bitartrate monohydrate (Standard)	Adrenergic Receptor Autophagy Endogenous Metabolite	Cardiovascular Disease Endocrinology Cancer
Norepinephrine (bitartrate monohydrate) (Standard) is the analytical standard of Norepinephrine (bitartrate monohydrate). This product is intended for research and analytical applications. Norepinephrine (Levarterenol; L-Noradrenaline) bitartrate monohydrate is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors ^[1] .

HY-106720A

Amosulalol hydrochloride YM 09538 hydrochloride	Adrenergic Receptor	Cardiovascular Disease
Amosulalol (YM 09538) hydrochloride is an orally active and dual inhibitor of α1/β1-Adrenergic Receptor. Amosulalol hydrochloride exhibits antihypertensive activity via α1-Adrenergic Receptor inhibition. Amosulalol hydrochloride decreases reflexogenic increases in heart rate and plasma renin activity (PRA) via β1-Adrenergic Receptor inhibition in spontaneously hypertensive rats (SHR) ^[1].

HY-17498B

Atenolol hydrochloride (RS)-Atenolol hydrochloride; Tenormin hydrochloride; ICI 66082 hydrochloride	Adrenergic Receptor	Cardiovascular Disease Neurological Disease Endocrinology Cancer
Atenolol hydrochloride is a cardioselective β1-adrenergic receptor blocker, with a K_i of 697 nM at β1-adrenoceptor in guine pig left ventricle membrane. Atenolol hydrochloride can be used for the research of hypertension and angina pectoris ^[1] .

HY-103214

Bucindolol	Adrenergic Receptor	Cardiovascular Disease Endocrinology
Bucindolol is a β1-adrenergic receptor blocker, with intrinsic sympathomimetic activity, used in the research of heart failure ^[1].

HY-17498

Atenolol 10+ Cited Publications (RS)-Atenolol	Adrenergic Receptor	Cardiovascular Disease Neurological Disease Endocrinology Cancer
Atenolol ((RS)-Atenolol) is a cardioselective β1-adrenergic receptor blocker, with a K_i of 697 nM at β1-adrenoceptor in guine pig left ventricle membrane. Atenolol can be used for the research of hypertension and angina pectoris ^[1] .

HY-165495

Pafenolol	Adrenergic Receptor	Cardiovascular Disease
Pafenolol is a selectively oral-active β1 adrenergic receptor (β1-adrenergic *receptor*) antagonist that effectively lowers blood pressure. Pharmacokinetic studies in rats indicate that the absorption of Pafenolol is influenced by gastrointestinal contents, with food intake reducing the bioavailability of Pafenolol in rats. Pafenolol can be used in research related to cardiovascular diseases and asthma ^[1].

HY-119802

Practolol	Adrenergic Receptor	Cardiovascular Disease
Practolol is a potent and selective β1-adrenergic receptor antagonist. Practolol can be used for the research of cardiac arrhythmias ^[1] .

HY-17498S

Atenolol-d7 (RS)-Atenolol-d₇	Adrenergic Receptor	Neurological Disease Endocrinology
Atenolol-d₇ is the deuterium labeled Atenolol. Atenolol ((RS)-Atenolol) is a cardioselective β1-adrenergic receptor blocker, with a Ki of 697 nM atβ1-adrenoceptor in guine pig left ventricle membrane. Atenolol can be used for the research of hypertension and angina pectoris[1][2].

HY-101327

Xamoterol Corwin; ICI 118587	Adrenergic Receptor	Cardiovascular Disease
Xamoterol is a selective and potent agonist of **beta1-adrenergic receptor*. Xamoterol has the potential for the research of arrhythmogenesis. Xamoterol has the potential for the investigating the relationship between β1-adrenergic* stimulation and IKr ^[1].

HY-13713

LY377604	Adrenergic Receptor	Metabolic Disease Endocrinology
LY377604 is a human β₃-adrenergic receptor agonist with an EC₅₀ of 2.4 nM and also a β₁- and β₂-adrenergic *receptor* antagonist.

HY-17498R

Atenolol (Standard) 10+ Cited Publications (RS)-Atenolol (Standard)	Adrenergic Receptor	Neurological Disease Endocrinology Cancer
Atenolol (Standard) is the analytical standard of Atenolol. This product is intended for research and analytical applications. Atenolol ((RS)-Atenolol) is a cardioselective β1-adrenergic receptor blocker, with a K_i of 697 nM atβ1-adrenoceptor in guine pig left ventricle membrane. Atenolol can be used for the research of hypertension and angina pectoris ^[1] .

HY-W752055

(Rac)-Nebivolol-d4 hydrochloride (Rac)-R 065824-d₄ hydrochloride	Adrenergic Receptor	Cardiovascular Disease Endocrinology
(Rac)-Nebivolol-d4 hydrochloride is a labelled racemic Nebivolol. Nebivolol selectively inhibits β1-adrenergic receptor with an IC₅₀ of 0.8 nM ^[1] .

HY-129436

(S)-Bucindolol	Adrenergic Receptor	Cardiovascular Disease
(S)-Bucindolol is the (S)-isomer of Bucindolol (HY-103214), a **β₁-adrenergic receptor** blocker. (S)-Bucindolol can be utilized in research on cardiac failure ^[1].

HY-15726

ICI 89406	Adrenergic Receptor	Metabolic Disease
ICI 89406 is a selective β1 adrenergic receptor antagonist amenable to labelling with positron emitters, for PET ^[1] .

HY-101327A

Xamoterol hemifumarate Corwin hemifumarate; ICI 118587 hemifumarate	Adrenergic Receptor	Cardiovascular Disease
Xamoterol hemifumarate is a selective and potent agonist of **beta1-adrenergic receptor*. Xamoterol hemifumarate has the potential for the research of arrhythmogenesis. Xamoterol hemifumarate has the potential for the investigating the relationship between β1-adrenergic* stimulation and IKr ^[1].

HY-P3557

Mibenratide	Adrenergic Receptor	Cardiovascular Disease
Mibenratide, a small cyclic peptide, is an **adrenergic β1 receptor** antagonist. Mibenratide can be used for heart failure research ^[1].

HY-119802S

Practolol-d7	Isotope-Labeled Compounds Adrenergic Receptor	Cardiovascular Disease
Practolol-d₇ is the deuterium labeled Practolol. Practolol is a potent and selective β1-adrenergic receptor antagonist. Practolol can be used for the research of cardiac arrhythmias[1][2][3].

HY-B0076S

Bisoprolol-d7 hemifumarate	Adrenergic Receptor	Inflammation/Immunology Endocrinology
Bisoprolol-d₇ (hemifumarate) is the deuterium labeled Bisoprolol hemifumarate. Bisoprolol hemifumarate is a selective type β1 adrenergic receptor blocker.

HY-P3557A

Mibenratide TFA	Adrenergic Receptor	Cardiovascular Disease
Mibenratide TFA, a small cyclic peptide, is an **adrenergic β1 receptor** antagonist. Mibenratide TFA can be used for heart failure research ^[1].

HY-129029

Bisoprolol 5+ Cited Publications	Adrenergic Receptor	Cardiovascular Disease Inflammation/Immunology Cancer
Bisoprolol is a potent, selective and orally active β1-adrenergic receptor blocker with little activity on β2-receptor. Bisoprolol has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research ^[1] .

HY-120829

Bisoprolol fumarate	Adrenergic Receptor	Cardiovascular Disease Inflammation/Immunology Cancer
Bisoprolol fumarate is a potent, selective and orally active β1-adrenergic receptor blocker with little activity on β2-receptor. Bisoprolol fumarate has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research ^[1] .

HY-17497A

Acebutolol hydrochloride 3 Publications Verification	Adrenergic Receptor	Cardiovascular Disease Endocrinology
Acebutolol hydrochloride is an orally active β1 adrenergic receptor (β1AR) antagonist. Acebutolol hydrochloride is used in the treatment of hypertension, angina pectoris and cardiac arrhythmias ^[1] .

HY-119802R

Practolol (Standard)	Adrenergic Receptor	Cardiovascular Disease
Practolol (Standard) is the analytical standard of Practolol. This product is intended for research and analytical applications. Practolol is a potent and selective β1-adrenergic receptor antagonist. Practolol can be used for the research of cardiac arrhythmias ^[1] .

HY-19012

N-1518	Adrenergic Receptor	Cardiovascular Disease
N-1518 is an α and β adrenergic receptor blocker that has competitive antagonism against β1 and α1 receptors, but does not show selectivity for β1 receptors, but shows about 20-fold selectivity for α1 receptors. N-1518 has vasodilatory effects and can be used in the research field of hypertension treatment ^[1].

HY-B0076

Bisoprolol hemifumarate 5+ Cited Publications	Adrenergic Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
Bisoprolol hemifumarate is a potent, selective and orally active β1-adrenergic receptor blocker with little activity on β2-receptor. Bisoprolol hemifumarate has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research ^[1] .

HY-108286

Talinolol Cordanum	Adrenergic Receptor	Cardiovascular Disease
Talinolol (Cordanum) is a long-acting, cardioselective β1-adrenergic receptor blocker. Talinolol exhibits cardioprotective and antihypertensive activities. Talinolol is also a well-known and frequently used probe substrate for P-glycoprotein (P-gp) activity ^[1] .

HY-B0203BS1

(rac)-Nebivolol-d4	Adrenergic Receptor	Cardiovascular Disease Endocrinology
(rac)-Nebivolol-d₄ is a labelled racemic Nebivolol. Nebivolol selectively inhibits β1- adrenergic receptor with IC50 of 0.8 nM[1][2].

HY-106684

Ridazolol	Adrenergic Receptor	Cardiovascular Disease
Ridazolol is a β-adrenergic receptor (βAR) antagonist. Ridazolol exhibits a high degree of selectivity for **β-1 adrenergic receptor** (β1AR) and possesses moderate intrinsic sympathomimetic activity (ISA). Ridazolol can competitively antagonize the relaxation effects induced by isoproterenol. Ridazolol is utilized in the research of cardiovascular diseases ^[1].

HY-106684A

Ridazolol hydrochloride	Adrenergic Receptor	Cardiovascular Disease
Ridazolol hydrochloride is a β-adrenergic receptor (βAR) antagonist. Ridazolol hydrochloride exhibits a high degree of selectivity for **β-1 adrenergic receptor** (β1AR) and possesses moderate intrinsic sympathomimetic activity (ISA). Ridazolol hydrochloride can competitively antagonize the relaxation effects induced by isoproterenol. Ridazolol hydrochloride is utilized in the research of cardiovascular diseases ^[1].

HY-121186

Bevantolol hydrochloride	Adrenergic Receptor Calcium Channel	Cardiovascular Disease Neurological Disease Metabolic Disease
Bevantolol hydrochloride is a selective β1 and α1-adrenergic receptor antagonist with pK_i values of 7.83, 6.9 in rat cerebral cortex, respectively. Bevantolol hydrochloride is a potent Ca ²⁺ antagonist ^[1] .

HY-17497S

Acebutolol-d7	Isotope-Labeled Compounds Adrenergic Receptor	Cardiovascular Disease Endocrinology
Acebutolol-d₇ is a deuterium labeled Acebutolol. Acebutolol is a selective β1 adrenergic receptor antagonist used in the treatment of hypertension, angina pectoris and cardiac arrhythmias[1].

HY-100672

SR59230A 5+ Cited Publications	Adrenergic Receptor	Cardiovascular Disease Metabolic Disease
SR59230A is a potent, selective, and blood-brain barrier penetrating β3-adrenergic receptor antagonist ^[1] with IC₅₀s of 40, 408, and 648 nM for β3, β1, and β2 receptors, respectively .

HY-103200

SR59230A hydrochloride 5+ Cited Publications	Adrenergic Receptor	Cardiovascular Disease Metabolic Disease
SR59230A hydrochloride is a potent, selective, and blood-brain barrier penetrating β3-adrenergic receptor antagonist ^[1] with IC₅₀s of 40, 408, and 648 nM for β3, β1, and β2 receptors, respectively .

HY-129029S

Bisoprolol-d5	Isotope-Labeled Compounds Adrenergic Receptor	Cardiovascular Disease
Bisoprolol-d₅ is the deuterium labeled Bisoprolol. Bisoprolol is a potent, selective and orally active β1-adrenergic receptor blocker. Bisoprolol has little activity on β2-receptor and has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research[1][2].

HY-13951

Zenidolol hydrochloride Maximum Cited Publications 35 Publications Verification ICI-118551 hydrochloride	Adrenergic Receptor	Neurological Disease Endocrinology
Zenidolol (ICI-118551) hydrochloride is a highly selective β2 adrenergic receptor antagonist, with K_is of 0.7, 49.5 and 611 nM for β2, β1 and β3 receptors, respectively.

HY-129029R

Bisoprolol (Standard)	Adrenergic Receptor	Cardiovascular Disease Inflammation/Immunology Cancer
Bisoprolol (Standard) is the analytical standard of Bisoprolol. This product is intended for research and analytical applications. Bisoprolol is a potent, selective and orally active β1-adrenergic receptor blocker with little activity on β2-receptor. Bisoprolol has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research ^[1] .

HY-139727

S(-)-Bisoprolol	Adrenergic Receptor	Cardiovascular Disease
S(-)-Bisoprolol is a S(-)-enantiomer of Bisoprolol. Bisoprolol is a potent, selective and orally active β1-adrenergic receptor blocker. Bisoprolol has little activity on β2-receptor and has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research ^[1] .

HY-139727A

S(-)-Bisoprolol fumarate	Adrenergic Receptor	Cardiovascular Disease
S(-)-Bisoprolol fumarate is a S(-)-enantiomer of Bisoprolol fumarate. Bisoprolol fumarate is a potent, selective and orally active β1-adrenergic receptor blocker. Bisoprolol has little activity on β2-receptor and has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research ^[1] .

HY-100543

Zenidolol ICI-118551	Adrenergic Receptor	Inflammation/Immunology
Zenidolol (ICI-118551) is a selective β2 adrenergic receptor antagonist. Zenidolol inhibits β2-, β1- and β3-adrenergic receptor with K_i values of 0.7, 49.5 and 611 nM, respectively. Zenidolol can be used as an ocular hypotensive agent used for ophthalmic disease research ^[1].

HY-123012A

Lubabegron fumarate LY-591281; LY-488756 fumarate	Androgen Receptor	Metabolic Disease
Lubabegron (LY-488756) fumarate is an antagonist of the adrenergic receptor (β-AR). Lubabegron fumarate can antagonize the stimulatory effects of *β1-AR* and β2-AR agonists on lipase respectively ^[1].

HY-108286S

(Rac)-Talinolol-d5	Isotope-Labeled Compounds Adrenergic Receptor	Cardiovascular Disease
(Rac)-Talinolol-d₅ is the racemate of Talinolol. Talinolol (Cordanum) is a long-acting, cardioselective β1-adrenergic receptor blocker. Talinolol exhibits cardioprotective and antihypertensive activities. Talinolol is also a well-known and frequently used probe substrate for P-glycoprotein (P-gp) activity[1][2][3].

HY-17497AR

Acebutolol hydrochloride (Standard)	Adrenergic Receptor	Cardiovascular Disease Endocrinology
Acebutolol (hydrochloride) (Standard) is the analytical standard of Acebutolol (hydrochloride). This product is intended for research and analytical applications. Acebutolol hydrochloride is an orally active β1 adrenergic receptor (β1AR) antagonist. Acebutolol hydrochloride is used in the treatment of hypertension, angina pectoris and cardiac arrhythmias ^[1] .

HY-13715S

(Rac)-Norepinephrine-d3 formate	Isotope-Labeled Compounds Endogenous Metabolite Adrenergic Receptor Autophagy	Cardiovascular Disease Endocrinology
(Rac)-Norepinephrine-d₃ (formate) is deuterium labeled Norepinephrine. Norepinephrine (Levarterenol; L-Noradrenaline) is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors[1][2][3][4].

Cat. No.	Product Name	Target	Research Area

HY-P3557

Mibenratide	Adrenergic Receptor	Cardiovascular Disease
Mibenratide, a small cyclic peptide, is an **adrenergic β1 receptor** antagonist. Mibenratide can be used for heart failure research ^[1].

HY-P3557A

Mibenratide TFA	Adrenergic Receptor	Cardiovascular Disease
Mibenratide TFA, a small cyclic peptide, is an **adrenergic β1 receptor** antagonist. Mibenratide TFA can be used for heart failure research ^[1].

HY-P10336

Serpinin	Peptides	Neurological Disease Endocrinology
Serpinin is an agonist of the protease inhibitor Nexin-1 (PN-1). Serpinin upregulates the expression of PN-1 through the cAMP-PKA-Sp1 signaling pathway, promoting granule biogenesis in endocrine cells. Serpinin is used in research related to the regulation of secretory function ^[1]. Serpinin is a selective agonist for β-adrenergic receptors. Serpinin interacts with β1-adrenergic receptors to activate the AC-cAMP-PKA pathway, which regulates myocardial systolic and diastolic function. pGlu-serpinin upregulates Bcl2 mRNA transcription and exerts neuroprotective effects .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-13715A

Norepinephrine hydrochloride Maximum Cited Publications 32 Publications Verification Levarterenol hydrochloride; L-Noradrenaline hydrochloride	Cardiovascular Disease Alkaloids Classification of Application Fields Mimosa pudica Linn. Leguminosae Other Alkaloids Source classification Phenols Polyphenols Plants Disease Research Fields Endocrinology	Adrenergic Receptor Autophagy Endogenous Metabolite
Norepinephrine (Levarterenol; L-Noradrenaline) hydrochloride is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α₁, α₂, β₁ receptors ^[1] .

HY-13715

Norepinephrine Maximum Cited Publications 32 Publications Verification Levarterenol; L-Noradrenaline	Cardiovascular Disease Structural Classification Classification of Application Fields Phenols Polyphenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite Adrenergic Receptor Autophagy
Norepinephrine (Levarterenol; L-Noradrenaline) is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α₁, α₂, β₁ receptors ^[1] .

HY-13715B

Norepinephrine bitartrate monohydrate Maximum Cited Publications 32 Publications Verification Levarterenol bitartrate monohydrate; L-Noradrenaline bitartrate monohydrate	Structural Classification Classification of Application Fields Source classification Phenols Endogenous metabolite Disease Research Fields Endocrinology	Adrenergic Receptor Autophagy Endogenous Metabolite
Norepinephrine (Levarterenol; L-Noradrenaline) bitartrate monohydrate is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α₁, α₂, β₁ receptors ^[1] .

HY-13715C

Norepinephrine tartrate Maximum Cited Publications 32 Publications Verification Levarterenol tartrate; L-Noradrenaline tartrate	Cardiovascular Disease Structural Classification Classification of Application Fields Source classification Phenols Polyphenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite Adrenergic Receptor Autophagy
Norepinephrine (Levarterenol; L-Noradrenaline) tartrate is a potent adrenergic receptor (AR) agonist. Norepinephrine tartrate activates α₁, α₂, β₁ receptors ^[1] .

HY-13715R

Norepinephrine (Standard) Levarterenol (Standard); L-Noradrenaline (Standard)	Structural Classification Phenols Polyphenols Endogenous metabolite	Endogenous Metabolite Adrenergic Receptor Autophagy
Norepinephrine (Standard) is the analytical standard of Norepinephrine. This product is intended for research and analytical applications. Norepinephrine (Levarterenol; L-Noradrenaline) is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α₁, α₂, β₁ receptors ^[1] .

HY-B0573

Propranolol hydrochloride 20+ Cited Publications	Alkaloids Neurological Disease Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Endocrinology	Adrenergic Receptor Bacterial
Propranolol hydrochloride is a nonselective *β-adrenergic* receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with K_i values of 1.8 nM and 0.8 nM, respectively ^[1]. Propranolol hydrochloride inhibits [ ³H]-DHA binding to rat brain membrane preparation with an IC₅₀** of 12 nM . Propranolol hydrochloride is used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .

HY-B0573B

Propranolol 20+ Cited Publications	Cardiovascular Disease Alkaloids Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Adrenergic Receptor Bacterial
Propranolol is a nonselective *β-adrenergic* receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with K_i values of 1.8 nM and 0.8 nM, respectively ^[1]. Propranolol inhibits [ ³H]-DHA binding to rat brain membrane preparation with an IC₅₀** of 12 nM . Propranolol is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .

HY-13715BR

Norepinephrine bitartrate monohydrate (Standard)	Structural Classification Source classification Phenols Endogenous metabolite	Adrenergic Receptor Autophagy Endogenous Metabolite
Norepinephrine (bitartrate monohydrate) (Standard) is the analytical standard of Norepinephrine (bitartrate monohydrate). This product is intended for research and analytical applications. Norepinephrine (Levarterenol; L-Noradrenaline) bitartrate monohydrate is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors ^[1] .

HY-B0573R

Propranolol hydrochloride (Standard)	Alkaloids Other Alkaloids Source classification Endogenous metabolite	Adrenergic Receptor Bacterial
Propranolol (hydrochloride) (Standard) is the analytical standard of Propranolol (hydrochloride). This product is intended for research and analytical applications. Propranolol hydrochloride is a nonselective *β-adrenergic* receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with K_i values of 1.8 nM and 0.8 nM, respectively ^[1]. Propranolol hydrochloride inhibits [ ³H]-DHA binding to rat brain membrane preparation with an IC₅₀** of 12 nM . Propranolol hydrochloride is used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .

Cat. No.	Product Name	Chemical Structure

HY-17498S

Atenolol-d7
Atenolol-d₇ is the deuterium labeled Atenolol. Atenolol ((RS)-Atenolol) is a cardioselective β1-adrenergic receptor blocker, with a Ki of 697 nM atβ1-adrenoceptor in guine pig left ventricle membrane. Atenolol can be used for the research of hypertension and angina pectoris[1][2].

HY-W752055

(Rac)-Nebivolol-d4 hydrochloride
(Rac)-Nebivolol-d4 hydrochloride is a labelled racemic Nebivolol. Nebivolol selectively inhibits β1-adrenergic receptor with an IC₅₀ of 0.8 nM ^[1] .

HY-119802S

Practolol-d7
Practolol-d₇ is the deuterium labeled Practolol. Practolol is a potent and selective β1-adrenergic receptor antagonist. Practolol can be used for the research of cardiac arrhythmias[1][2][3].

HY-B0076S

Bisoprolol-d7 hemifumarate
Bisoprolol-d₇ (hemifumarate) is the deuterium labeled Bisoprolol hemifumarate. Bisoprolol hemifumarate is a selective type β1 adrenergic receptor blocker.

HY-B0203BS1

(rac)-Nebivolol-d4
(rac)-Nebivolol-d₄ is a labelled racemic Nebivolol. Nebivolol selectively inhibits β1- adrenergic receptor with IC50 of 0.8 nM[1][2].

HY-17497S

Acebutolol-d7
Acebutolol-d₇ is a deuterium labeled Acebutolol. Acebutolol is a selective β1 adrenergic receptor antagonist used in the treatment of hypertension, angina pectoris and cardiac arrhythmias[1].

HY-129029S

Bisoprolol-d5
Bisoprolol-d₅ is the deuterium labeled Bisoprolol. Bisoprolol is a potent, selective and orally active β1-adrenergic receptor blocker. Bisoprolol has little activity on β2-receptor and has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research[1][2].

HY-108286S

(Rac)-Talinolol-d5
(Rac)-Talinolol-d₅ is the racemate of Talinolol. Talinolol (Cordanum) is a long-acting, cardioselective β1-adrenergic receptor blocker. Talinolol exhibits cardioprotective and antihypertensive activities. Talinolol is also a well-known and frequently used probe substrate for P-glycoprotein (P-gp) activity[1][2][3].

HY-13715S

(Rac)-Norepinephrine-d3 formate
(Rac)-Norepinephrine-d₃ (formate) is deuterium labeled Norepinephrine. Norepinephrine (Levarterenol; L-Noradrenaline) is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors[1][2][3][4].

HY-B0203BS2

(Rac)-Nebivolol-d2,15N

(Rac)-Nebivolol-d₂, ¹⁵N is ¹⁵N and deuterated labeled (Rac)-Nebivolol (HY-B0203B). (Rac)-Nebivolol ((Rac)-R 065824) is a racemic isomer of Nebivolol. Nebivolol is a selective β1-adrenergic receptor antagonist with an IC₅₀ value of 0.8 nM. Nebivolol can prevent up-regulation of Nox2/NADPH oxidase and lipoperoxidation in the early stages of ethanol-induced cardiac toxicity. Vasodilatory activity ^[1] .

HY-100634S

4-Hydroxypropranolol-d7 hydrochloride

4-Hydroxypropranolol-d₇ (hydrochloride) is a deuterium labeled 4-Hydroxypropranolol hydrochloride. 4-Hydroxypropranolol hydrochlorid is an active metabolite of Propranolol, with potency comparable to Propranolol. 4-Hydroxypropranolol hydrochlorid inhibits β1- and β2-adrenergic receptors with pA2 values of 8.24 and 8.26, respectively. 4-Hydroxypropranolol hydrochlorid has intrinsic sympathomimetic activity, membrane stabilizing activity and potent antioxidant properties[1][2][3].

HY-100935S

Cimaterol-d7
Cimaterol-d₇ is the deuterium labeled Cimaterol. Cimaterol is a potent agonist of β-adrenergic receptors (pEC50s=8.13, 8.78, and 6.62 for human β1, β2, and β3, respectively). Cimaterol has been used in farmed animals to increase carcass mass and to alter muscle and fat deposition.

HY-100634SA

4-Hydroxypropranolol-d7

4-Hydroxypropranolol-d₇ is the deuterium labeled 4-Hydroxypropranolol hydrochloride. 4-Hydroxypropranolol hydrochlorid is an active metabolite of Propranolol. 4-Hydroxypropranolol hydrochlorid is of comparable potency to Propranolol. 4-Hydroxypropranolol hydrochlorid inhibits β1- and β2-adrenergic receptors with pA2 values of 8.24 and 8.26, respectively. 4-Hydroxypropranolol hydrochlorid has intrinsic sympathomimetic activity, membrane stabilizing activity and potent antioxidant properties[1][2][3].

HY-B0381S

Betaxolol-d5
Betaxolol-d₅ is the deuterium labeled Betaxolol. Betaxolol is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma.

HY-B0381AS

Betaxolol-d7 hydrochloride
Betaxolol-d₇ (hydrochloride) is the deuterium labeled Betaxolol hydrochloride. Betaxolol Hydrochloride is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma.

HY-B0573BS

Propranolol-d7

Propranolol-d₇ is the deuterium labeled Propranolol. Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively[1]. Propranolol inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM[2]. Propranolol is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy[3].

HY-B0573S

Propranolol-d7 hydrochloride

Propranolol-d₇ (hydrochloride) is a deuterium labeled Propranolol hydrochloride. Propranolol hydrochloride is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively[1]. Propranolol hydrochloride inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM[2]. Propranolol hydrochloride is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy[3].

HY-B0573S1

Propranolol-d7 (ring-d7)

Propranolol-d₇ (ring-d₇) is the deuterium labeled Propranolol hydrochloride. Propranolol hydrochloride is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively[1]. Propranolol hydrochloride inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM[2]. Propranolol hydrochloride is used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy[3].

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