(Rac)-Nebivolol-d₄ hydrochloride (Synonyms: (Rac)-R 065824-d₄ hydrochloride)

Cat. No.: HY-W752055: FAQs
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(Rac)-Nebivolol-d4 hydrochloride is a labelled racemic Nebivolol. Nebivolol selectively inhibits β1-adrenergic receptor with an IC₅₀ of 0.8 nM.

For research use only. We do not sell to patients.

(Rac)-Nebivolol-d<sub>4</sub> hydrochloride Chemical Structure

(Rac)-Nebivolol-d₄ hydrochloride Chemical Structure

CAS No. : 2701283-32-9

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1 mg		Get quote	Estimated Time of Arrival: December 31

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α adrenergic receptor β adrenergic receptor

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Description	(Rac)-Nebivolol-d4 hydrochloride is a labelled racemic Nebivolol. Nebivolol selectively inhibits β1-adrenergic receptor with an IC₅₀ of 0.8 nM^[1]^[2]^[3].
Molecular Weight	445.92
Formula	C₂₂H₂₂D₄ClF₂NO₄
CAS No.	2701283-32-9
SMILES	[2H]C(NC([2H])(C(C1CCC2=C(O1)C=CC(F)=C2)O)[2H])(C(C3CCC4=CC(F)=CC=C4O3)O)[2H].Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (266 KB) Handling Instructions (2659 KB)
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief] [2]. Brehm BR, et al. Effects of nebivolol on proliferation and apoptosis of human coronary artery smooth muscle and endothelial cells. Cardiovasc Res. 2001 Feb 1;49(2):430-9. [Content Brief] [3]. Mercanoglu G, et al. The effects of nebivolol on apoptosis in a rat infarct model. Circ J. 2008 Apr;72(4):660-70. [Content Brief]

(Rac)-Nebivolol-d₄ hydrochloride Related Classifications

Endocrinology Cardiovascular Disease

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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(Rac)-Nebivolol-d₄2701283-32-9(Rac)-R 065824-d₄Adrenergic ReceptorBeta ReceptorInhibitorinhibitorinhibit

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(Rac)-Nebivolol-d4 hydrochloride (Synonyms: (Rac)-R 065824-d4 hydrochloride)

Other Forms of (Rac)-Nebivolol-d4 hydrochloride:

(Rac)-Nebivolol-d4 hydrochloride Related Antibodies

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(Rac)-Nebivolol-d4 hydrochloride Related Classifications