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Results for "

SPI-0211

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0679
    Lubiprostone
    1 Publications Verification

    RU-0211; SPI-0211

    		 Chloride Channel CFTR Glutathione Peroxidase NO Synthase TNF Receptor Metabolic Disease
    Lubiprostone (SPI-0211; RU0211) increases intestinal fluid secretion through generation of CIC-2/CFTR and activation of cAMP signaling pathway. Lubiprostone inhibits myeloperoxidase (MPO) activity, downregulates Indomethacin (HY-14397)-induced iNOS and TNFα expression. Lubiprostone can be used for chronic constipation research .
    Lubiprostone
  • HY-B0679R
    Lubiprostone (Standard)

    RU-0211 (Standard); SPI-0211 (Standard)

    		 Chloride Channel CFTR Glutathione Peroxidase NO Synthase TNF Receptor Metabolic Disease
    Lubiprostone (Standard) is the analytical standard of Lubiprostone. This product is intended for research and analytical applications. Lubiprostone (SPI-0211; RU0211) increases intestinal fluid secretion through generation of CIC-2/CFTR and activation of cAMP signaling pathway. Lubiprostone inhibits myeloperoxidase (MPO) activity, downregulates Indomethacin (HY-14397)-induced iNOS and TNFα expression. Lubiprostone can be used for chronic constipation research[1][2][3].
    Lubiprostone (Standard)
  • HY-B0680
    Lubiprostone (hemiketal)

    RU-0211 (hemiketal); SPI-0211 (hemiketal)

    		 Chloride Channel Others Cancer
    Lubiprostone (hemiketal) (RU-0211 (hemiketal)) is a selective chloride channel 2 (CLCN2) activator. Lubiprostone (hemiketal) is used to treat chronic idiopathic constipation and opioid-induced constipation by activating CLCN2 channels to increase chloride ion secretion in the intestine, thereby increasing intestinal fluid secretion and enhancing intestinal peristalsis. Lubiprostone (hemiketal) can be used in the study of chronic constipation and cancer .
    Lubiprostone (hemiketal)
  • HY-B0679S
    Lubiprostone-d7

    RU-0211-d7; SPI-0211-d7

    		 Chloride Channel Metabolic Disease
    Lubiprostone-d7 (RU-0211-d7) is the deuterium labeled Lubiprostone. Lubiprostone (RU0211) is a gastrointestinal agent used for the treatment of idiopathic chronic constipation[1][2].
    Lubiprostone-d7