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1-Bromo-4-(ethynyloxy)butane

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-169992

    PROTAC Linkers Others
    1-Bromo-4-(ethynyloxy)butane is the PROTAC linker of ACBI3 (HY-157228) and can be used in the synthesis of PROTACs .
    1-Bromo-4-(ethynyloxy)butane
  • HY-157228

    PROTACs Others Cancer
    ACBI3 (compound 7) is a PROTAC targeting KRAS. ACBI3 is composed of PROTAC target protein ligand pan-KRAS degrader 1 (HY-162960) (red part), E3 ligase ligand E3 ligase Ligand 43 (HY-401613) (blue part) and PROTAC Linker 1-Bromo-4-(ethynyloxy)butane (HY-169992) (black part), among which the conjugate of E3 ubiquitin ligase ligand + Linker is E3 Ligase Ligand-linker Conjugate 143 (HY-169995) .
    ACBI3

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