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1-Methylxanthine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CD38 (1) CFTR (2) Drug Metabolite (3) Endogenous Metabolite (6) Ferroportin (1) Isotope-Labeled Compounds (1) MMP (1) Phosphodiesterase (PDE) (2) Tyrosinase (1) Vasopressin Receptor (1)
By Research Areas:	Cancer (7) Infection (1) Inflammation/Immunology (2) Metabolic Disease (2)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W008449

*1-Methylxanthine*	Drug Metabolite Endogenous Metabolite	Cancer
1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP) ^[1]. 1-Methylxanthine enhances the radiosensitivity of tumor cells .

HY-12318G

IBMX 3-Isobutyl-1-Methylxanthine; IsobutylMethylxanthine	Phosphodiesterase (PDE)	Inflammation/Immunology
IBMX (3-Isobutyl-1-methylxanthine) (GMP) is IBMX (HY-12318) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. IBMX is a broad-spectrum phosphodiesterase (PDE) inhibitor ^[1] .

HY-12318

IBMX 35+ Cited Publications 3-Isobutyl-1-Methylxanthine; IsobutylMethylxanthine	Phosphodiesterase (PDE)	Inflammation/Immunology
IBMX is a broad-spectrum phosphodiesterase (PDE) inhibitor, with IC₅₀s of 6.5, 26.3 and 31.7 μM for PDE3, PDE4 and PDE5, respectively.

HY-W008449R

1-Methylxanthine (Standard)	Drug Metabolite Endogenous Metabolite	Cancer
1-Methylxanthine (Standard) is the analytical standard of 1-Methylxanthine. This product is intended for research and analytical applications. 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP) ^[1]. 1-Methylxanthine enhances the radiosensitivity of tumor cells .

HY-W008449S2

1-Methylxanthine-d3	Drug Metabolite Endogenous Metabolite Isotope-Labeled Compounds	Cancer
1-Methylxanthine-d₃ is deuterated labeled 1-Methylxanthine (HY-W008449). 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP) ^[1]. 1-Methylxanthine enhances the radiosensitivity of tumor cells .

HY-W008449S

1-Methylxanthine-13C,d3	Endogenous Metabolite	Cancer
1-Methylxanthine- ¹³C,d₃ is the ¹³C- and deuterium labeled 1-Methylxanthine. 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP)[1]. 1-Methylxanthine enhances the radiosensitivity of tumor cells[2].

HY-W008449S1

1-Methylxanthine-13C4,15N3	Endogenous Metabolite	Cancer
1-Methylxanthine- ¹³C₄, ¹⁵N₃ is the ¹³C-labeled and ¹⁵N-labeled 1-Methylxanthine. 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP)[1]. 1-Methylxanthine enhances the radiosensitivity of tumor cells[2].

HY-N3773

Dodoviscin A	Tyrosinase	Cancer
Dodoviscin A is a pigmentation-altering agent, which can be isolated from the aerial parts of Dodonaea viscosa. Dodoviscin A inhibits melanin production in B16-F10 melanoma cells. Dodoviscin A suppresses mushroom tyrosinase activity, and tyrosinase activity induced by 3-isobutyl-1-methylxanthine. Dodoviscin A also inhibits the phorphosylation of cAMP response element binding protein, induced by 3-isobutyl-1-methylxanthine and forskolin ^[1].

HY-W017163S

*7-Methylxanthine-2,4,5,6-13C4, 1,3-15N2 (with variable 15N labeling at N9)*	Endogenous Metabolite	Metabolic Disease
7-Methylxanthine-2,4,5,6- ¹³C₄, 1,3- ¹⁵N₂ (with variable ¹⁵N labeling at N₉) is the ¹³C and ¹⁵N labeled 7-Methylxanthine[1]. 7-Methylxanthine, a methyl derivative of xanthine, is one of the purine components in urinary calculi[2].

HY-P1108

Astressin 2B	CFTR	Others
Astressin 2B is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC₅₀ values of 1.3 nM and > 500 nM for CRF2 and *CRF1, respectively. Astressin 2B antagonizes CRF2*-mediated inhibition of gastric emptying ^[1] .

HY-P1108A

Astressin 2B TFA	CFTR	Others
Astressin 2B TFA is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC₅₀ values of 1.3 nM and > 500 nM for CRF2 and *CRF1, respectively. Astressin 2B TFA antagonizes CRF2*-mediated inhibition of gastric emptying ^[1] .

HY-P4521

*Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt*	MMP	Others
Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt is a MMP12 substrate, and can be used to detect MMP12 enzyme activity ^[1].

HY-P3066

SKF 100398 d(CH2)5Tyr(Et)VAVP	Vasopressin Receptor	Metabolic Disease
SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP ^[1].

HY-P10272

Rusfertide PTG-300	Ferroportin	Others
Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis ^[1] .

HY-P10563

Noraramtide BHV-1100	CD38	Cancer
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity ^[1].

Cat. No.	Product Name	Type

HY-12318G

IBMX (GMP) 3-Isobutyl-1-Methylxanthine (GMP); IsobutylMethylxanthine (GMP)	Fluorescent Dye
IBMX (3-Isobutyl-1-methylxanthine) (GMP) is IBMX (HY-12318) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. IBMX is a broad-spectrum phosphodiesterase (PDE) inhibitor ^[1] .

Cat. No.	Product Name	Type

HY-12318G

IBMX (GMP) 3-Isobutyl-1-Methylxanthine (GMP); IsobutylMethylxanthine (GMP)	Biochemical Assay Reagents
IBMX (3-Isobutyl-1-methylxanthine) (GMP) is IBMX (HY-12318) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. IBMX is a broad-spectrum phosphodiesterase (PDE) inhibitor ^[1] .

Cat. No.	Product Name	Target	Research Area

HY-P1108A

Astressin 2B TFA	CFTR	Others
Astressin 2B TFA is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC₅₀ values of 1.3 nM and > 500 nM for CRF2 and *CRF1, respectively. Astressin 2B TFA antagonizes CRF2*-mediated inhibition of gastric emptying ^[1] .

HY-P3066

SKF 100398 d(CH2)5Tyr(Et)VAVP	Vasopressin Receptor	Metabolic Disease
SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP ^[1].

HY-P10272

Rusfertide PTG-300	Ferroportin	Others
Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis ^[1] .

HY-P4756

*N-(2-Carbamoyl-ethyl)-Val-Leu-anilide*	Peptides	Others
N-(2-Carbamoyl-ethyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development ^[1].

HY-P1108

Astressin 2B	CFTR	Others
Astressin 2B is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC₅₀ values of 1.3 nM and > 500 nM for CRF2 and *CRF1, respectively. Astressin 2B antagonizes CRF2*-mediated inhibition of gastric emptying ^[1] .

HY-P2592

Ro 23-7014	Peptides	Others
Ro 23-7014 is an appetite suppressant. Ro 23-7014 is an analog of cholecystokinin (CCK-7) ^[1].

HY-P4521

*Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt*	MMP	Others
Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt is a MMP12 substrate, and can be used to detect MMP12 enzyme activity ^[1].

HY-125628

Kahalalide A	Peptides	Infection
Kahalalide A is an anti-mycobacterial compound with antimicrobial activity. Kahalalide A is derived from the marine mollusk Elysia rufescens. Kahalalide A has attracted extensive attention in natural product research due to its potential medicinal value ^[1].

HY-P10563

Noraramtide BHV-1100	CD38	Cancer
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity ^[1].

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W008449

*1-Methylxanthine*	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Drug Metabolite Endogenous Metabolite
1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP) ^[1]. 1-Methylxanthine enhances the radiosensitivity of tumor cells .

HY-W008449R

1-Methylxanthine (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Drug Metabolite Endogenous Metabolite
1-Methylxanthine (Standard) is the analytical standard of 1-Methylxanthine. This product is intended for research and analytical applications. 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP) ^[1]. 1-Methylxanthine enhances the radiosensitivity of tumor cells .

HY-N3773

Dodoviscin A	Structural Classification Flavonoids Flavones Source classification Dodonaea viscosa (L.) Jacq. Sapindaceae Plants	Tyrosinase
Dodoviscin A is a pigmentation-altering agent, which can be isolated from the aerial parts of Dodonaea viscosa. Dodoviscin A inhibits melanin production in B16-F10 melanoma cells. Dodoviscin A suppresses mushroom tyrosinase activity, and tyrosinase activity induced by 3-isobutyl-1-methylxanthine. Dodoviscin A also inhibits the phorphosylation of cAMP response element binding protein, induced by 3-isobutyl-1-methylxanthine and forskolin ^[1].

Cat. No.	Product Name	Chemical Structure

HY-W008449S2

1-Methylxanthine-d3
1-Methylxanthine-d₃ is deuterated labeled 1-Methylxanthine (HY-W008449). 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP) ^[1]. 1-Methylxanthine enhances the radiosensitivity of tumor cells .

HY-W008449S

1-Methylxanthine-13C,d3
1-Methylxanthine- ¹³C,d₃ is the ¹³C- and deuterium labeled 1-Methylxanthine. 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP)[1]. 1-Methylxanthine enhances the radiosensitivity of tumor cells[2].

HY-W008449S1

1-Methylxanthine-13C4,15N3
1-Methylxanthine- ¹³C₄, ¹⁵N₃ is the ¹³C-labeled and ¹⁵N-labeled 1-Methylxanthine. 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP)[1]. 1-Methylxanthine enhances the radiosensitivity of tumor cells[2].

HY-W017163S

*7-Methylxanthine-2,4,5,6-13C4, 1,3-15N2 (with variable 15N labeling at N9)*
7-Methylxanthine-2,4,5,6- ¹³C₄, 1,3- ¹⁵N₂ (with variable ¹⁵N labeling at N₉) is the ¹³C and ¹⁵N labeled 7-Methylxanthine[1]. 7-Methylxanthine, a methyl derivative of xanthine, is one of the purine components in urinary calculi[2].

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1-Methylxanthine

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

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Isotope-Labeled Compounds

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