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Results for "

4-Hydroxyphenylacetic acid

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

1

Peptides

4

Natural
Products

2

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N1902
    4-Hydroxyphenylacetic acid

    		Keap1-Nrf2 Endogenous Metabolite Metabolic Disease
    4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2 .
    4-Hydroxyphenylacetic acid
  • HY-N1902S
    4-Hydroxyphenylacetic acid-d6

    		Keap1-Nrf2 Endogenous Metabolite Metabolic Disease
    4-Hydroxyphenylacetic acid-d6 is the deuterium labeled 4-Hydroxyphenylacetic acid. 4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2[1].
    4-Hydroxyphenylacetic acid-d6
  • HY-W001146
    3-Chloro-4-hydroxyphenylacetic acid

    		Drug Intermediate Metabolic Disease
    3-Chloro-4-hydroxyphenylacetic acid is a fungal metabolite. 3-Chloro-4-hydroxyphenylacetic acid is an active small molecule, that can be used as building block in synthesis of 17β-HSD2 inhibitors .
    3-Chloro-4-hydroxyphenylacetic acid
  • HY-W001084
    Methyl 4-hydroxyphenylacetate

    		Drug Derivative Others
    Methyl 4-hydroxyphenylacetate, a natural compound, is a methyl ester resulting from the formal condensation of the carboxy group of 4-Hydroxyphenylacetic acid with methanol .
    Methyl 4-hydroxyphenylacetate
  • HY-N1902R
    4-Hydroxyphenylacetic acid (Standard)

    		Keap1-Nrf2 Endogenous Metabolite Metabolic Disease
    4-Hydroxyphenylacetic acid (Standard) is the analytical standard of 4-Hydroxyphenylacetic acid. This product is intended for research and analytical applications. 4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2 . IC50 & Target:Nrf2 In Vivo: 4-Hydroxyphenylacetic acid (6, 12, or 25 mg/kg) increases Nrf2 translocation to the nucleus and enhances the activity of phase II and antioxidant enzymes. The protein levels of nuclear Nrf2 are increased by 170% and 230% in pre-treated 12 and 25 mg/kg 4-Hydroxyphenylacetic acid groups, respectively, compared with the control group.The 4-Hydroxyphenylacetic acid pretreatment at a final dose of 25 mg/kg markedly and selectively up-regulated the target genes of phase II enzymes and resulted in higher up-regulation than that of the control group by 270%, 400%, and 500% or UGT1A1, UGT1A9, and SULT2A1, respectively. 4-Hydroxyphenylacetic acid also suppresses the expression of CYP2E1 .
    4-Hydroxyphenylacetic acid (Standard)
  • HY-N1902S1
    4-Hydroxyphenylacetic acid-d4

    		Keap1-Nrf2 Endogenous Metabolite Metabolic Disease
    4-Hydroxyphenylacetic acid-d4 is the deuterium labeled 4-Hydroxyphenylacetic acid[1]. 4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2[2].
    4-Hydroxyphenylacetic acid-d4
  • HY-W001084R
    Methyl 4-hydroxyphenylacetate (Standard)

    		Drug Derivative Others
    Methyl 4-hydroxyphenylacetate (Standard) is the analytical standard of Methyl 4-hydroxyphenylacetate. This product is intended for research and analytical applications. Methyl 4-hydroxyphenylacetate, a natural compound, is a methyl ester resulting from the formal condensation of the carboxy group of 4-Hydroxyphenylacetic acid with methanol[1].
    Methyl 4-hydroxyphenylacetate (Standard)
  • HY-P10563
    Noraramtide

    BHV-1100

    		 CD38 Cancer
    Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .
    Noraramtide

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