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Results for "

A 61603

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-101366
    A-61603

    		Adrenergic Receptor Cardiovascular Disease
    A-61603 is a selective α1A-adrenergic receptor agonist . A-61603 increases the frequency of spontaneous Ca 2+ transients in rat ventricular myocytes in vitro .
    A-61603
  • HY-P5881
    PKCα (C2-4) inhibitor peptide

    		PKC Cardiovascular Disease
    PKCα (C2-4) inhibitor peptide is a PKCα specific inhibitor peptide that blocks the inhibition of IKr by the α1A adrenoreceptor agonist A-61603 (HY-101366) .
    PKCα (C2-4) inhibitor peptide
  • HY-119883
    A-61603 (free base）

    		Adrenergic Receptor Neurological Disease
    A-61603 free base is a potent adrenergic receptor agonist. A-61603 free base reduces carotid artery conductance in anesthetized pigs mediated by α1 and α2 adrenergic receptors (pEC50=7.25). A-61603 free base can be used as a probe to study adrenergic function .
    A-61603 (free base）
  • HY-U00237B
    L-771688 hydrochloride

    		Others Others
    L-771688 hydrochloride is a potent and highly selective α1A-adrenoceptor antagonist (Kd=43-90 pM). L-771688 hydrochloride is effective against cloned human, rat and dog α1A-adrenergic receptors. L-771688 exhibits high affinity (Ki ≤ 1 nM) and over 500-fold selectivity over the α1B and α1D isoforms. L-771688 potently antagonizes norepinephrine-induced responses at these receptors. Inhibits contractions induced by phenylephrine or A-61603 in rat, dog, human and monkey models .
    L-771688 hydrochloride

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