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Results for "

ALC0315

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

4

Biochemical Assay Reagents

10

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-138170
    ALC-0315
    10+ Cited Publications

    		 Liposome SARS-CoV Infection
    ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
    ALC-0315
  • HY-153380
    ALC-0315 analogue-2

    		Liposome Others
    ALC-0315 analogue-2 is an analogue of ALC-0315. ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine.
    ALC-0315 analogue-2
  • HY-153379
    ALC-0315 analogue-1

    		Liposome Others
    ALC-0315 analogue-1 (compound P-10) is a cationic lipid. ALC-0315 analogue-1 is the raw material for synthesis of cationic liposome .
    ALC-0315 analogue-1
  • HY-153389
    ALC-0315 analogue-3

    		Liposome Others
    ALC-0315 analogue-3 (compound P-35) is a liposome raw material. ALC-0315 analogue-3 can improve the loading rate and transport rate of nucleic acid drugs .
    ALC-0315 analogue-3
  • HY-138170A
    ALC-0315 (Excipient)

    		Liposome SARS-CoV Infection
    ALC-0315 Excipient is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 Excipient can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
    ALC-0315 (Excipient)
  • HY-W440800
    BP Lipid 226

    		Liposome Cancer
    BP Lipid 226 is an amino ionizable lipid analogous to ALC-0315. It can be used to prepare liposome or lipid nanoparticles.
    BP Lipid 226
  • HY-W800777
    6-(3-Hydroxypropylamino)hexyl 2-hexyldecanoate

    		Liposome Cancer
    6-(3-Hydroxypropylamino)hexyl 2-hexyldecanoate is an ionizable lipid which can be used to make ALC-0315. The lipid has an ester bond adjacent to C6 relative to the amine nitrogen. The introduction of ester linkages can improve the clearance of the lipid in the liver.
    6-(3-Hydroxypropylamino)hexyl 2-hexyldecanoate
  • HY-W440802
    BP Lipid 217

    		Liposome Others
    BP Lipid 217 is derived from patent WO2023178065A2 (B32). BP Lipid 217 is an ethanolamine ionizable lipid with both ester bonds located adjacent to C8 relative to the amine head. The introduction of ester linkages can improve the clearance of the lipid in the liver. This compound is analgous to ALC-0315.
    BP Lipid 217
  • HY-W800849
    BP Lipid 315

    		Liposome Cancer
    BP Lipid 315 is a cationic ionizable lipid ALC-0315 analogue featuring a Boc-protected primary amine, a central tertiary amine, and two ester tails located at the C8 position relative to the amine. One of these esters features a symmetrical branched C17 tail, while the other is an asymmetric C11 tail.
    BP Lipid 315
  • HY-W800749
    BP Lipid 223

    		Liposome Cancer
    BP Lipid 223 is an pentanolamine lipid (Compound 7) from patent WO2017075531A with both ester bonds located adjacent to C6 relative to the amine head. The introduction of ester linkages can improve the clearance of the lipid in the liver. This compound is analgous to ALC-0315. The lipid can be used to prepare mRNA nanocarriers with good balance of delivery efficiency and pharmakokinetics as well as rapid lipid clearance profile.
    BP Lipid 223

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