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AP6

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Autophagy (1) Biochemical Assay Reagents (1) E3 Ligase Ligand-Linker Conjugates (1) iGluR (1) PARP (1) Potassium Channel (1) PROTAC Linkers (1) PROTACs (1)
By Research Areas:	Cancer (3) Neurological Disease (3)

Inhibitors & Agonists

Biochemical Assay Reagents

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-130644

iRucaparib-AP6 1 Publications Verification	PROTACs PARP	Cancer
iRucaparib-AP6 is a highly efficient and specific PROTAC PARP1 degrader. iRucaparib-AP6, a non-trapping PARP1 degrader, blocks both the catalytic activity and scaffolding effects of PARP1 .

HY-120918

NH2-PEG7	PROTAC Linkers	Cancer
NH2-PEG7 is a PROTAC linker, which refers to the PEG composition. NH2-PEG7 can be used in the synthesis of the PROTAC PARP1 degrader iRucaparib-AP6 .

HY-161949

*AP-6*	Potassium Channel	Neurological Disease
AP-6 is a selective inhibitor of TMEM175 with activity in modulating lysosomal function. Acute inhibition of TMEM175 by AP-6 increases lysosomal macromolecular catabolism, thereby accelerating macrophage and other digestive processes. AP-6 may be used in Parkinson's disease research .

HY-D0172

Tetrabutylammonium bromide AP 6G; Actiron 43-65; Aliquat 100	Biochemical Assay Reagents	Others
Tetrabutylammonium bromide is an organic ammonium compound, which is often used in catalytic reactions and separation and purification processes. It has a significant catalytic effect in some organic synthesis reactions, and can be used as a surfactant, stabilizer and antibacterial agent, etc. In addition, in some laboratory studies, this compound has also been used as an ion exchanger, solvent extractant, etc.

HY-100843

L-AP6	Others	Neurological Disease
L-AP6 is a selective agonist for a quisqualate-sensitized site in hippocampal CA1 pyramidal neurons .

HY-100781

D-AP4 D-APB; D-2-Amino-4-phosphonobutyric acid	iGluR	Neurological Disease
D-AP4 (D-APB; D-2-Amino-4-phosphonobutyric acid), a phosphono analogue of glutamate, is an NMDA broad spectrum excitatory amino acid receptor antagonist. D-AP4 also is an agonist for a quisqualate-sensitized AP6 site in hippocampus. D-AP4 inhibits AMPA receptor-stimulated 57Co ²⁺ influx in cultured cerebellar granule cells (IC₅₀ ≥ 100 μM) .

HY-130648

Thalidomide-NH-PEG7	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-NH-PEG7 is a synthesized E3 ligase ligand-linker conjugate for ADC. Thalidomide-NH-PEG7 can be connected to the ligand for protein by a linker to form PROTAC iRucaparib-AP6, a highly specific PARP1 degrader .

Cat. No.	Product Name	Type

HY-D0172

Tetrabutylammonium bromide AP 6G; Actiron 43-65; Aliquat 100	Biochemical Assay Reagents
Tetrabutylammonium bromide is an organic ammonium compound, which is often used in catalytic reactions and separation and purification processes. It has a significant catalytic effect in some organic synthesis reactions, and can be used as a surfactant, stabilizer and antibacterial agent, etc. In addition, in some laboratory studies, this compound has also been used as an ion exchanger, solvent extractant, etc.

Tetrabutylammonium bromide

AP 6G; Actiron 43-65; Aliquat 100

Biochemical Assay Reagents

Tetrabutylammonium bromide is an organic ammonium compound, which is often used in catalytic reactions and separation and purification processes. It has a significant catalytic effect in some organic synthesis reactions, and can be used as a surfactant, stabilizer and antibacterial agent, etc. In addition, in some laboratory studies, this compound has also been used as an ion exchanger, solvent extractant, etc.

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