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Results for "

APA

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (1) ADC Cytotoxin (1) Aminopeptidase (4) Bacterial (3) COX (1) Cytochrome P450 (1) DNA/RNA Synthesis (1) Drug Metabolite (2) Endogenous Metabolite (1) Histone Acetyltransferase (1) HIV (2) HSP (1) Leukotriene Receptor (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (3) Infection (6) Inflammation/Immunology (2)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W013549

6-Aminopenicillanic acid 6-APA	Drug Metabolite Bacterial	Infection Inflammation/Immunology
6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses .

HY-145954

NAT2-IN-1 APA	Histone Acetyltransferase	Cancer
NAT2-IN-1 (APA) is an inhibitor of agent metabolic enzyme N-acetyltransferase 2 (NAT2). NAT2-IN-1 can selectively kill slow NAT2 cells .

HY-115828

APA-APA-MPO dihydrochloride	HIV	Infection
APA-APA-MPO dihydrochloride is an inhibitor of PCAF bromodomain/Tat-AcK50 interaction with reduced cytotoxic activity. APA-APA-MPO dihydrochloride can effectively inhibit the binding of PCAF to Tat-AcK50, showing its potential in HIV/AIDS inhibitory strategies. APA-APA-MPO dihydrochloride can be used in studies that hinder HIV replication .

HY-115829

APA-H-MPO hydrochloride	HIV	Infection
APA-H-MPO hydrochloride is an inhibitor of PCAF bromodomain/Tat-AcK50 interaction with potential for anti-HIV/AIDS. APA-H-MPO hydrochloride can effectively inhibit the binding of PCAF bromodomain to Tat-AcK50. APA-H-MPO hydrochloride showed low cytotoxicity in preliminary cell studies. APA-H-MPO hydrochloride is considered a potential candidate for a promising inhibitory strategy targeting the host cell protein PCAF BRD to block HIV replication .

HY-130997

*17-GMB-APA-GA*	ADC Cytotoxin HSP	Infection Cancer
17-GMB-APA-GA is an ADC Cytotoxin. 17-GMB-APA-GA is a potent HSP90 inhibitor and used for latent T. gondii infection research .

HY-W747565

Leukotriene B4-3-aminopropylamide LTB4-APA	Leukotriene Receptor	Inflammation/Immunology
Leukotriene B4-3-aminopropylamide (LTB4-APA) is a leukotriene immunomodulator .

HY-162920

QGC583	Aminopeptidase	Cardiovascular Disease
QGC583 is an effective selective Aminopeptidase A (APA) inhibitor with oral activity and blood-brain barrier permeability, boasting an IC₅₀ value of 4 nM. QGC583 can inhibit *APA* activity in the brain, kidneys, and heart of rats .

HY-W014674

2,6-Dichlorophenylacetic acid	Acyltransferase	Cancer
2,6-Dichlorophenylacetic acid is an inhibitor of isopenicillin N synthase (IPNS) and *acyl-CoA: 6-APA* acyltransferase**. 2,6-Dichlorophenylacetic acid is also part of a group of phenylacetate derivatives that have cytostatic activity against tumour cells .

HY-129298

Amastatin	Aminopeptidase	Others
Amastatin is A slow, tightly bound, competitive inhibitor of aminopeptidase (AP) with an IC₅₀ of 0.54 μg/mL for AP-A .

HY-115451

Photoregulin 3	DNA/RNA Synthesis	Others
Photoregulin 3 (compound T4) can promote distal-to-proximal alternative polyadenylation (APA) activity in multiple transcripts .

HY-162574

CYP11B2-IN-2	Cytochrome P450	Cancer
CYP11B2-IN-2 (Compound 10k) is an inhibitor for enzyme aldosterone synthase CYP11B2 with an IC₅₀ of 0.3 nM. CYP11B2-IN-2 CYP11B-IN-2 is labeled with 18F and can be used as a positron emission tomography (PET) tracer for the diagnosis of primary aldosteronism .

HY-N7067

Revaprazan hydrochloride 1 Publications Verification	Bacterial COX	Infection
Revaprazan hydrochloride is a novel acid pump antagonist (APA). Revaprazan hydrochloride reduces COX-2 expression and has significant anti-inflammatory actions activities in H. pylori infection .

HY-E70318

AMK-GX Immobilized Penicillin G acylase	Endogenous Metabolite	Others
AMK-GX (Immobilized Penicillin G acylase) is an immobilized penicillin acylase with improved temperature and pH stability. AMK-GX has reusable performance and high recovery rates, retaining much of its original activity after 12 cycles. Among them, AMK-GX can catalyze penicillin G (PG) to generate 6-aminopenicillanic acid (6-APA) and 7-aminodeacetoxycephalosporanic acid, which are key intermediates for β-lactam antibiotics .

HY-W013549R

6-Aminopenicillanic acid (Standard)	Drug Metabolite Bacterial	Infection
6-Aminopenicillanic acid (Standard) is the analytical standard of 6-Aminopenicillanic acid. This product is intended for research and analytical applications. 6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses .

HY-W717329

EC33	Aminopeptidase	Cardiovascular Disease
EC33 is a selective aminopeptidase A (APA) inhibitor. EC33 blocks the pressor response of exogenous Ang II. EC33 does not cross the blood-brain barrier. EC33 has the potential for salt-dependent model of hypertension research .

HY-109058

Firibastat 1 Publications Verification QGC001; RB150	Aminopeptidase	Cardiovascular Disease
Firibastat (QGC001), an orally active brain penetrating proagent of EC33, is a first-in-class brain aminopeptidase A (APA) inhibitor (K_i=200 nM). Firibastat selectively and specifically inhibits conversion of brain angiotensin-II into angiotensin-III and decreases blood pressure in hypertensive rats .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W013549

6-Aminopenicillanic acid 6-APA	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Drug Metabolite Bacterial
6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses .

HY-W013549R

6-Aminopenicillanic acid (Standard)	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Drug Metabolite Bacterial
6-Aminopenicillanic acid (Standard) is the analytical standard of 6-Aminopenicillanic acid. This product is intended for research and analytical applications. 6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses .

Species:	Human (1) Rat (1) Mouse (1)
Tag:	His (3)
Source:	Sf9 insect cells (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P72826

	Aminopeptidase A Protein, Rat (sf9, His) Glutamyl aminopeptidase; EAP; AP-A; CD249; ENPEP	Rat	Sf9 insect cells
	Aminopeptidase A, modulated by calcium, regulates central hypertension by preferentially cleaving N-terminal acidic residues from peptides, including angiotensin II. Aminopeptidase A Protein, Rat (sf9, His) is the recombinant rat-derived Aminopeptidase A protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of Aminopeptidase A Protein, Rat (sf9, His) is 905 a.a., with molecular weight of ~116 kDa.

HY-P72824

	Aminopeptidase A Protein, Human (sf9, His) Glutamyl aminopeptidase; EAP; AP-A; CD249; ENPEP	Human	Sf9 insect cells
	Aminopeptidase A protein has calcium-regulating activity and plays a key role in central hypertension by preferentially cleaving N-terminal acidic residues, including angiotensin II. The specificity of this enzyme highlights its involvement in the regulation of blood pressure-related peptides, suggesting potential implications for the physiological mechanisms of hypertension. Aminopeptidase A Protein, Human (sf9, His) is the recombinant human-derived Aminopeptidase A protein, expressed by Sf9 insect cells , with N-His labeled tag.

HY-P72825

	Aminopeptidase A Protein, Mouse (sf9, His) Glutamyl aminopeptidase; EAP; AP-A; CD249; ENPEP	Mouse	Sf9 insect cells
	The aminopeptidase A protein is a key player in the regulation of central hypertension, exerting its effects by selectively cleaving the N-terminal acidic residues of peptides such as angiotensin II. The enzyme's preference for specific substrates is regulated by calcium levels, underscoring its critical role in controlling blood pressure and maintaining cardiovascular health. Aminopeptidase A Protein, Mouse (sf9, His) is the recombinant mouse-derived Aminopeptidase A protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of Aminopeptidase A Protein, Mouse (sf9, His) is 905 a.a., with molecular weight of ~113 kDa.

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HY-P82419

	AP-A Antibody (YA2164) AP-A; Aminopeptidase A; APA; bp1; CD249; EAP; Enpep; Gp160; Ly51	WB, IHC-P	Human
	AP-A Antibody (YA2164) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2164), targeting AP-A, with a predicted molecular weight of 109 kDa (observed band size: 160 kDa). AP-A Antibody (YA2164) can be used for WB, IHC-P experiment in human background.

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APA

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