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Results for "

Aristolochic

" in MedChemExpress (MCE) Product Catalog:

17

Inhibitors & Agonists

1

Biochemical Assay Reagents

15

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0511
    Aristolochic acid B
    1 Publications Verification

    		 Others Cancer
    Aristolochic acid B is one of the major components of Aristolochic acids (AA) which are natural products derived from taxa in the Aristolochiaceae. Aristolochic acid is known to be a potent mutagen and carcinogen. Aristolochic acid B showes more carcinogenic risk than Aristolochic acid A in vivo .
    Aristolochic acid B
  • HY-N1465
    Aristolochic acid D

    		Others Cancer
    Aristolochic acid D is an aristolochic acid derivative isolated from stems of Aristolochia indica. Aristolochic acid is nephrotoxin and carcinogen .
    Aristolochic acid D
  • HY-N0510
    Aristolochic acid A
    Maximum Cited Publications
    9 Publications Verification

    Aristolochic acid I; TR 1736

    		 NF-κB Cancer
    Aristolochic acid A (Aristolochic acid I; TR 1736) is the main component of plant extract Aristolochic acids, which are found in various herbal plants of genus Aristolochia and Asarum. Aristolochic acid A significantly reduces both activator protein 1 (AP-1) and NF-κB activities. Aristolochic acid A reduces BLCAP gene expression in human cell lines .
    Aristolochic acid A
  • HY-N1450
    Aristolochic acid C

    		Phospholipase Cancer
    Aristolochic acid C is a derivative of Aristolochic acid. Aristolochic acid is a phospholipase A2 (PLA2) inhibitor, which disrupts cortical microtubule arrays and root growth in Arabidopsis .
    Aristolochic acid C
  • HY-N1465R
    Aristolochic acid D (Standard)

    		Others Cancer
    Aristolochic acid D (Standard) is the analytical standard of Aristolochic acid D. This product is intended for research and analytical applications. Aristolochic acid D is an aristolochic acid derivative isolated from stems of Aristolochia indica. Aristolochic acid is nephrotoxin and carcinogen .
    Aristolochic acid D (Standard)
  • HY-N0511R
    Aristolochic acid B (Standard)

    		Others Cancer
    Aristolochic acid B (Standard) is the analytical standard of Aristolochic acid B. This product is intended for research and analytical applications. Aristolochic acid B is one of the major components of Aristolochic acids (AA) which are natural products derived from taxa in the Aristolochiaceae. Aristolochic acid is known to be a potent mutagen and carcinogen. Aristolochic acid B showes more carcinogenic risk than Aristolochic acid A in vivo .
    Aristolochic acid B (Standard)
  • HY-N0510R
    Aristolochic acid A (Standard)

    		NF-κB Cancer
    Aristolochic acid A (Standard) is the analytical standard of Aristolochic acid A. This product is intended for research and analytical applications. Aristolochic acid A (Aristolochic acid I; TR 1736) is the main component of plant extract Aristolochic acids, which are found in various herbal plants of genus Aristolochia and Asarum. Aristolochic acid A significantly reduces both activator protein 1 (AP-1) and NF-κB activities. Aristolochic acid A reduces BLCAP gene expression in human cell lines .
    Aristolochic acid A (Standard)
  • HY-N1450R
    Aristolochic acid C (Standard)

    		Phospholipase Cancer
    Aristolochic acid C (Standard) is the analytical standard of Aristolochic acid C. This product is intended for research and analytical applications. Aristolochic acid C is a derivative of Aristolochic acid. Aristolochic acid is a phospholipase A2 (PLA2) inhibitor, which disrupts cortical microtubule arrays and root growth in Arabidopsis .
    Aristolochic acid C (Standard)
  • HY-N11445
    Aristolochic acid Va

    		Others Others
    Aristolochic acid Va is a natural compound that can be isolated from Aristolochia plants .
    Aristolochic acid Va
  • HY-N7951
    Aristolochic acid III

    		Others Others
    Aristolochic acid III is a natural product that can be isolated from the leaves of Aristolochia debilis .
    Aristolochic acid III
  • HY-N0510A
    Aristolochic acid sodium salt
    Maximum Cited Publications
    9 Publications Verification

    Aristolochic acid I sodium; TR 1736 sodium; Sodium aristolochate

    		 Biochemical Assay Reagents Others
    Aristolochic acid sodium salt (Sodium aristolate 1) is a component of some Chinese herbal medicines and is responsible for nephrotoxicity. It is a proagent that is activated by reduction of nitro groups to amines, resulting in the formation of cytotoxic DNA adducts.
    Aristolochic acid sodium salt
  • HY-N2012
    7-Hydroxyaristolochic acid A

    		Others Inflammation/Immunology
    7-Hydroxyaristolochic acid A is an aristolochic acid analogue found in Aristolochia plants. Aristolochic acid can be used as an anti-inflammatory agent .
    7-Hydroxyaristolochic acid A
  • HY-N11562
    Aristololactam II

    		Others Others
    Aristololactam II, a metabolite of Aristolochic acid II (AAII), is an excretion product found in the urine, which is considered to be detoxification metabolite of AAII .
    Aristololactam II
  • HY-N2013
    Aristolactam I
    1 Publications Verification

    Aristololactam; Aristolactam

    		 Caspase Apoptosis Inflammation/Immunology
    Aristololactam I (AL-I), is the main metabolite of aristolochic acid I (AA-I), participates in the processes that lead to renal damage. Aristololactam I (AL-I) directly injures renal proximal tubule cells, the cytotoxic potency of AL-I is higher than that of AA-I and that the cytotoxic effects of these molecules are mediated through the induction of apoptosis in a caspase-3-dependent pathway .
    Aristolactam I
  • HY-135772
    12-Ketodeoxycholic acid

    12-Ketolithocholic acid

    		 Endogenous Metabolite Metabolic Disease
    12-Ketodeoxycholic acid (12-Ketolithocholic acid) is a bile acid, metabolite from kidney. 12-Ketodeoxycholic acid can be a detectable marker for evidence of kidney injury
    12-Ketodeoxycholic acid
  • HY-N2013R
    Aristolactam I (Standard)

    		Caspase Apoptosis Inflammation/Immunology
    Aristolactam I (Standard) is the analytical standard of Aristolactam I. This product is intended for research and analytical applications. Aristololactam I (AL-I), is the main metabolite of aristolochic acid I (AA-I), participates in the processes that lead to renal damage. Aristololactam I (AL-I) directly injures renal proximal tubule cells, the cytotoxic potency of AL-I is higher than that of AA-I and that the cytotoxic effects of these molecules are mediated through the induction of apoptosis in a caspase-3-dependent pathway .
    Aristolactam I (Standard)
  • HY-114740
    β-Naphthoflavone
    1 Publications Verification

    5,6-Benzoflavone; beta-NF

    		 Aryl Hydrocarbon Receptor Apoptosis Neurological Disease Cancer
    β-Naphthoflavone is an exogenous aryl hydrocarbon receptor (AHR) ligand. β-Naphthoflavone can activate AHR to participate in various biological processes, including cell growth, differentiation, apoptosis, and metabolism. β-Naphthoflavone has antioxidant activity and can exert its antioxidant function by regulating the activity of antioxidant enzymes. β-Naphthoflavone is also a non-carcinogenic CYP1A inducer and can be used to treat aristolochic acid (AAI) induced renal injury .
    β-Naphthoflavone

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