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Isoforms Recommended: CCR9
Results for "

CCR9

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

3

Recombinant Proteins

1

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15724
    Vercirnon
    3 Publications Verification

    GSK-1605786; CCX282-B; Traficet-EN

    CCR Inflammation/Immunology Endocrinology
    Vercirnon (GSK1605786A) is an orally bioavailable, selective, and potent antagonist of CCR9. Vercirnon inhibits CCR9-mediated Ca 2+ mobilization and chemotaxis on Molt-4 cells with IC50 values of 5.4 and 3.4 nM, respectively. Vercirnon is selective for CCR9 over CCR1-12 and CX3CR1-7 (IC50s>10 µM for all). Vercirnon is an equipotent inhibitor of CCL25-directed chemotaxis of both splice forms of CCR9 (CCR9A and CCR9B) with IC50 values of 2.8 and 2.6 nM, respectively .
    Vercirnon
  • HY-15724A
    Vercirnon sodium
    3 Publications Verification

    GSK-1605786 sodium; CCX282-B sodium; Traficet-EN sodium

    CCR Inflammation/Immunology Endocrinology
    Vercirnon (GSK1605786A) sodium is an orally bioavailable, selective, and potent antagonist of CCR9. Vercirnon sodium inhibits CCR9-mediated Ca 2+ mobilization and chemotaxis on Molt-4 cells with IC50 values of 5.4 and 3.4 nM, respectively. Vercirnon sodium is selective for CCR9 over CCR1-12 and CX3CR1-7 (IC50s>10 µM for all). Vercirnon sodium is an equipotent inhibitor of CCL25-directed chemotaxis of both splice forms of CCR9 (CCR9A and CCR9B) with IC50 values of 2.8 and 2.6 nM, respectively .
    Vercirnon sodium
  • HY-123763

    CCR Inflammation/Immunology
    MLN3126 is an orally active and potent CCR9 antagonist. MLN3126 inhibits CCL25-induced calcium mobilization and chemotaxis of mouse primary thymocytes, wiht an IC50 value of 6.3 nM for calcium influx .
    MLN3126
  • HY-RS02172

    Small Interfering RNA (siRNA) Others

    CCR9 Human Pre-designed siRNA Set A contains three designed siRNAs for CCR9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CCR9 Human Pre-designed siRNA Set A
    CCR9 Human Pre-designed siRNA Set A
  • HY-RS02173

    Small Interfering RNA (siRNA) Others

    Ccr9 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ccr9 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Ccr9 Mouse Pre-designed siRNA Set A
    Ccr9 Mouse Pre-designed siRNA Set A
  • HY-RS02174

    Small Interfering RNA (siRNA) Others

    Ccr9 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ccr9 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Ccr9 Rat Pre-designed siRNA Set A
    Ccr9 Rat Pre-designed siRNA Set A
  • HY-113545

    9(R)-Hydroxyoctadecadienoic acid

    Endogenous Metabolite Metabolic Disease
    9(R)-HODE is a monohydroxy fatty acid and metabolite of linoleic acid. It is formed from linoleic acid by COX and lipoxygenase (LO).9(R)-HODE induces chemotaxis, increases the levels of chemokine (C-C motif) receptor 9 (CCR9) and chemokine (C-X-C motif) receptor 4 (CXCR4), and inhibits IL-6 release in primary human monocytes. It inhibits CD3α- and CD28-induced proliferation of isolated human peripheral blood lymphocytes when used at a concentration of 25 μg/mL.
    9(R)-HODE

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