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Pathways Recommended:	Antibody-drug Conjugate/ADC Related

Results for "

CD27 Antibody

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Drug Derivative (1) Influenza Virus (1) TNF Receptor (7)
By Research Areas:	Cancer (5) Inflammation/Immunology (5)

9

Inhibitors & Agonists

7

Inhibitory Antibodies

2

Antibodies

Targets Recommended: ADC Antibody Antibody-Drug Conjugates (ADCs) ADC Linker PROTAC-Linker Conjugates for PAC

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Varlilumab (anti-CD27)	TNF Receptor	Cancer
Varlilumab (anti-CD27) is a first-in-class human IgG1 anti-CD27 monoclonal antibody. Varlilumab has an anti-tumor activity .

Boserolimab MK-5890	TNF Receptor	Cancer
Boserolimab (MK-5890) is a humanized agonist monoclonal antibody that binds to CD27 to provide a costimulatory signal that enhances T-cell–mediated responses .

Varlilumab CDX-1127	TNF Receptor	Cancer
Varlilumab (CDX-1127) is a first-in-class human IgG1 anti-CD27 monoclonal antibody. Varlilumab has an anti-tumor activity .

Cusatuzumab 1 Publications Verification ARGX-110	Apoptosis TNF Receptor	Inflammation/Immunology Cancer
Cusatuzumab (ARGX-110) is a human αCD70 monoclonal antibody. Cusatuzumab has the activity of enhancied antibody-dependent cellular cytotoxicity (ADCC). Cusatuzumab blocks the *CD70/CD27* signaling pathway, reduces leukemia stem cells (LSCs) and triggers gene signatures related to myeloid differentiation and apoptosis. Cusatuzumab can be used to study leukemia .

17-HDHA	Influenza Virus	Inflammation/Immunology
17-HDHA is a DHA-derived specialized proresolving mediator (SPM). 17-HDHA enhances the antibody-mediated immune response against influenza virus. 17-HDHA enhances the differentiation of B cells toward the CD27 ⁺ CD38 ⁺ antibody-secreting cell phenotype, thereby strongly increasing IgM and IgG production by activated B cells .

Anti-Mouse CD27 Antibody (RM27-3E5)	TNF Receptor	Others
Anti-Mouse CD27 Antibody (RM27-3E5) is a rat-derived IgG2a, κ type antibody inhibitor, targeting to mouse CD27.

Anti-TNFRSF7/CD27 Antibody	TNF Receptor	Inflammation/Immunology
Anti-TNFRSF7/CD27 Antibody is a CHO-expressed human antibody targeting *TNFRSF7/CD27. The Anti-TNFRSF7/CD27* Antibody contains huIgG2 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-TNFRSF7/CD27 Antibody can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

GEN-1053 BNT-313	TNF Receptor	Inflammation/Immunology Cancer
GEN-1053 (BNT-313) is a fully human IgG1 antibody that targets CD27. GEN-1053 binds to CD27 and forms a hexamer upon binding. The isotype control for GEN-1053 can refer to Human IgG1 lambda1, Isotype Control (HY-P99992) .

17(R)-HDHA 17(R)-HDoHE	Drug Derivative	Inflammation/Immunology
17(R)-HDHA (17(R)-HDoHE) is a pro-resolving mediator (SPM). 17(R)-HDHA enhances the differentiation of B cells toward the CD27(+)CD38(+) antibody-secreting cell phenotype, thereby strongly increasing IgM and IgG production by activated B cells. 17(R)-HDHA does not affect cell proliferation and is non-toxic to cells .

Cat. No.	Product Name	Target	Research Area

Varlilumab (anti-CD27)	TNF Receptor	Cancer
Varlilumab (anti-CD27) is a first-in-class human IgG1 anti-CD27 monoclonal antibody. Varlilumab has an anti-tumor activity .

Boserolimab MK-5890	TNF Receptor	Cancer
Boserolimab (MK-5890) is a humanized agonist monoclonal antibody that binds to CD27 to provide a costimulatory signal that enhances T-cell–mediated responses .

Varlilumab CDX-1127	TNF Receptor	Cancer
Varlilumab (CDX-1127) is a first-in-class human IgG1 anti-CD27 monoclonal antibody. Varlilumab has an anti-tumor activity .

Cusatuzumab 1 Publications Verification ARGX-110	Apoptosis TNF Receptor	Inflammation/Immunology Cancer
Cusatuzumab (ARGX-110) is a human αCD70 monoclonal antibody. Cusatuzumab has the activity of enhancied antibody-dependent cellular cytotoxicity (ADCC). Cusatuzumab blocks the *CD70/CD27* signaling pathway, reduces leukemia stem cells (LSCs) and triggers gene signatures related to myeloid differentiation and apoptosis. Cusatuzumab can be used to study leukemia .

Anti-Mouse CD27 Antibody (RM27-3E5)	TNF Receptor	Others
Anti-Mouse CD27 Antibody (RM27-3E5) is a rat-derived IgG2a, κ type antibody inhibitor, targeting to mouse CD27.

Anti-TNFRSF7/CD27 Antibody	TNF Receptor	Inflammation/Immunology
Anti-TNFRSF7/CD27 Antibody is a CHO-expressed human antibody targeting *TNFRSF7/CD27. The Anti-TNFRSF7/CD27* Antibody contains huIgG2 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-TNFRSF7/CD27 Antibody can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

GEN-1053 BNT-313	TNF Receptor	Inflammation/Immunology Cancer
GEN-1053 (BNT-313) is a fully human IgG1 antibody that targets CD27. GEN-1053 binds to CD27 and forms a hexamer upon binding. The isotype control for GEN-1053 can refer to Human IgG1 lambda1, Isotype Control (HY-P99992) .

Cat. No.	Compare	Product Name	Application	Reactivity

	CD70 Antibody (YA1409) CD70; CD27LG; TNFSF7; TNFSF7G; CD27L	FC, ELISA	Human
	CD70 Antibody (YA1409) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1409), targeting CD70. CD70 Antibody (YA1409) can be used for FC, ELISA experiment in human background.

	CD27 Antibody (YA1278) CD27; CD27L receptor; LPFS2; S152; T14; TNFRSF7; TNFSF7; Tp55	IHC-P	Human
	CD27 Antibody (YA1278) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1278), targeting CD27. CD27 Antibody (YA1278) can be used for IHC-P experiment in human background.

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