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Results for "

CEACAM1

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

4

Inhibitory Antibodies

10

Recombinant Proteins

3

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-163028
    ML-T7

    		Tim3 Cancer
    ML-T7 is a potent Tim-3 inhibitor. ML-T7 blocks Tim-3 interactions with PtdSer and CEACAM1. ML-T7 not only enhances the antitumor activity of adoptive transfer therapy with cytotoxic T lymphocytes (CTLs) and CAR T cells but also increases the effector function of T cell. ML-T7 promotes NK cells’ killing activity against tumor cells and DC antigen-presenting capacity. ML-T7 directly exerts antitumor efficacy in preclinical tumor models either alone or in combination with Nivolumab (HY-P9903A). ML-T7 can be used for tumor immunotherapy research [1].
    ML-T7
  • HY-155175
    TIM-3-IN-2

    		Tim3 Cancer
    TIM-3-IN-2 (Compound A-41) is a Tim3 inhibitor (KD: 0.61 μM). TIM-3-IN-2 blocks TIM-3 interactions with PtdSer, CEACAM1, and Gal-9. TIM-3-IN-2 inhibits the immunosuppressive function of TIM-3. TIM-3-IN-2 reverses the TIM-3-mediated blockade of the production of proinflammatory cytokines, and maximizes the T-cell antitumor activity against AML cell lines [1].
    TIM-3-IN-2
  • HY-RS02435
    CEACAM1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    CEACAM1 Human Pre-designed siRNA Set A contains three designed siRNAs for CEACAM1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CEACAM1 Human Pre-designed siRNA Set A
    CEACAM1 Human Pre-designed siRNA Set A
  • HY-P990364
    Anti-CEACAM1/CD66a Antibody

    		Transmembrane Glycoprotein Inflammation/Immunology
    Anti-CEACAM1/CD66a Antibody is a human antibody expressed in CHO cells that targets CEACAM1/CD66a. The Anti-CEACAM1/CD66a Antibody is equipped with huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 144.98 kDa. The isotype control for the Anti-CEACAM1/CD66a Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
    Anti-CEACAM1/CD66a Antibody
  • HY-P990854
    Anti-CEACAM1/3/5/6/8 Antibody (6G5j)

    		Transmembrane Glycoprotein Others
    Anti-CEACAM1/3/5/6/8 Antibody (6G5j) is a kind of mouse IgG1, κ chimeric antibody, targeting to human CEACAM1/3/5/6/8. The recommend isotype control of Anti-CEACAM1/3/5/6/8 Antibody (6G5j): Mouse IgG1 kappa, Isotype Control (HY-P99977).
    Anti-CEACAM1/3/5/6/8 Antibody (6G5j)
  • HY-159884
    MG-T-19

    		Tim3 TNF Receptor IFNAR Cancer
    MG-T-19 is an effective TIM-3 inhibitor that can suppress the interaction of TIM-3 with PtdSer, CEACAM1, and Gal-9. MG-T-19 can increase the production of tumor necrosis factor-α (TNF-α) and interferon-γ (IFN-γ) in peripheral blood mononuclear cells (PBMCs) from healthy donors, and enhance the ability of PBMCs to inhibit the proliferation of Kasumi-1 cells (an acute myelogenous leukemia cell line) [1].
    MG-T-19
  • HY-P991198
    M6903

    		Tim3 Cancer
    M6903 is a humanized monoclonal IgG2 antibody targeting T cell immunoglobulin and mucin domain-3 (TIM-3) (KD for human TIM-3 is 2.3 nM). M6903 binds to TIM-3, blocking the binding of TIM-3 to phosphatidylserine (PtdSer), carcinoembryonic antigen cell adhesion-related molecule 1 (CEACAM1), and galectin 9 (Gal-9), thus relieving TIM-3-mediated T cell inhibition and exerting the activities of activating antigen-specific T cells and enhancing anti-tumor immunity. M6903 is promising for research of cancers [1].
    M6903

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