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Results for "

CENPs

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-19530
    PF-2771

    		Kinesin Cancer
    PF-2771 is a potent and selective centromere protein E (CENP-E) inhibitor, inhibiting CENP-E motor activity with an IC50 of 16.1 nM; PF-2771 is used as an anticancer agent.
    PF-2771
  • HY-121569
    Syntelin

    		Kinesin Cancer
    Syntelin is a selective centromere protein E (CENP-E) inhibitor with IC50 at 160 nM. Syntelin has antitumor activity .
    Syntelin
  • HY-10299
    GSK-923295
    35+ Cited Publications

    		 Kinesin Apoptosis Cancer
    GSK-923295 is a special, allosteric inhibitor of centromere-associated protein-E (CENP-E) kinesin motor ATPase activity, with Ki of 3.2±0.2 nM and 1.6± 0.1 nM for human and canine, respectively.
    GSK-923295
  • HY-RS02490
    CENPS Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    CENPS Human Pre-designed siRNA Set A contains three designed siRNAs for CENPS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CENPS Human Pre-designed siRNA Set A
    CENPS Human Pre-designed siRNA Set A
  • HY-161898
    CENP-E-IN-3

    		Kinesin Cancer
    CENP-E-IN-3 (compound 4) is a potent CENP-E inhibitor. CENP-E-IN-3 has the potential for the research of cancer .
    CENP-E-IN-3
  • HY-161897
    CENP-E-IN-2

    		Kinesin Cancer
    CENP-E-IN-2 (compound 3) is a photoswitchable CENP-E inhibitor, with the pIC50 of 6.82 without light illumination and 5.85 with 365 nm light illumination. CENP-E-IN-2 has antitumor activity .
    CENP-E-IN-2
  • HY-163288
    EZH2/HSP90-IN-29

    		Histone Methyltransferase HSP Apoptosis Cancer
    EZH2/HSP90-IN-29 is a dual inhibitor for EZH2 and HSP90, with IC50s of 6.29 nM and 60.1 nM, for EZH2 and HSP90, respectively. EZH2/HSP90-IN-29 increases apoptosis/necrosis-related gene expression, induces cell cycle arrest at M phase and inhibits reactive oxygen species (ROS) catabolism pathway. EZH2/HSP90-IN-29 is able to cross the blood-brain-barrier (BBB) .
    EZH2/HSP90-IN-29
  • HY-110090
    UA62784

    		Microtubule/Tubulin Kinesin Apoptosis Cancer
    UA62784 is a microtubule polymerization inhibitor that interacts with tubulin dimers. UA62784 is a novel specific inhibitor of centromere protein E (CENP-E) kinesin. UA62784 can be used for the study of pancreatic cancer .
    UA62784
  • HY-150265
    TNH

    TMP-NVOC linker-Halo

    		 Kinesin Others
    TNH (TMP-NVOC linker-Halo) is a dimeric protein chemical inducer that can enter living cells and recruit proteins to cellular structures. TNH senses light signals and acts by recruiting proteins to kinetochores and releasing them from kinetochores (depending on CENP-E (kinesin-7)) .
    TNH

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