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Results for "

CFBE41o-

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-18337
    IOWH-032
    4 Publications Verification

    		 CFTR SARS-CoV Infection Metabolic Disease
    IOWH-032 is a a synthetic anti-secretory molecule, is a potent CFTR inhibitor with an IC50 value of 8 μM. IOWH-032 also is a anti-diarrheal agent .
    IOWH-032
  • HY-170515
    RNF5 agonist 1

    		E1/E2/E3 Enzyme Inflammation/Immunology
    RNF5 agonist 1 (analog-1), a structural analog of RNF5 inhibitor inh-02 (HY-123967), is a potent RNF5 agonist. RNF5 agonist 1 increases the ubiquitylation status of ATG4B in F508del-CFTR-expressing CFBE41o- cells .
    RNF5 agonist 1
  • HY-P10226
    PGD97

    		Chloride Channel CFTR Endocrinology
    PGD97 is a selective cyclic peptide inhibitor against CAL/CFTR interactions, with a KD value of 6 nM towards the CAL PDZ domain for its desulfide cyclized form. PGD97 (desulfide cyclized form) has selectivity ≥ 130-fold compared to NHERF1/2 PDZ domains. PGD97 is capable of stabilizing F508del-CFTR at the cell membrane and improving CFTR function required for proper fluid homeostasis in tne lung. PGD97 can be used for the research of cystic fibrosis .
    PGD97

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